Published on: 9/30/2024
The toxic range of acetaminophen (7,500 15,000mg) is much higher than the recommended one time dose range for an adult (1000mg). Most people do not have symptoms in the first 24 hours. If you are concerned you took too much acetaminophen, seek further medical evaluation.
The toxic range of acetaminophen (the dosage at which side effects are likely to occur) is much higher than the recommended dose range. Therefore, taking one or two extra tablets generally does not require further action or worry. Confirm the amount of acetaminophen taken. For adults, the amount that causes liver damage is around 150mg/kg, so a 50kg (110lbs) person would need to take 7,500mg. One tablet of acetaminophen typically contains 500mg, so you would have to ingest 15 tablets. Please be sure to follow the prescribed times for your next dose and avoid overmedication. If you have any pre-existing conditions or if you notice any concerning symptoms, please seek further medical attention. Early stages of acetaminophen toxicity are often asymptomatic and early intervention within 8 hours of ingestion with antidotes effectively eliminates the risk of liver toxicity.
(References)
Fisher ES, Curry SC. Evaluation and treatment of acetaminophen toxicity. Adv Pharmacol. 2019;85:263272. doi: 10.1016/bs.apha.2018.12.004. Epub 2019 Jan 22. PMID: 31307590.
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