Can acetaminophen cause allergic reactions like rashes or swelling?

Acetaminophen, also known as paracetamol, is a common medication used to relieve pain and reduce fever. While it is generally considered safe, some individuals may experience allergic reactions to it. These reactions can manifest as skin rashes, swelling, or more severe symptoms.

1. Mild Reactions: Some people might experience mild allergic reactions, such as skin rashes or hives.

2. Severe Reactions: In rare cases, acetaminophen can cause severe reactions like anaphylaxis, which is a serious and potentially life-threatening condition. Symptoms of anaphylaxis can include swelling of the face or throat, difficulty breathing, and a rapid drop in blood pressure.

The medical literature includes reports of such severe reactions. One study describes an anaphylactoid reaction, which is similar to anaphylaxis but does not involve the immune system in the same way. Another case report discusses acetaminophen-induced anaphylaxis. A third report highlights a case of anaphylactic shock caused by acetaminophen.

If you suspect an allergic reaction to acetaminophen, it is important to seek medical attention immediately, especially if symptoms are severe. Always consult a healthcare provider for advice specific to your health condition.