Our Services
Medical Information
Helpful Resources
Published on: 9/13/2026
Yes, both high-protein and very low-carb ketogenic diets can lead to an ammonia-like odor in sweat, because when your body breaks down more amino acids for fuel, excess nitrogen is converted to ammonia and some is released through the skin. Dehydration, intense or prolonged exercise, and low carbohydrate availability tend to make the smell stronger by concentrating waste products in sweat. Adjusting protein intake, adding some carbohydrates around workouts, and drinking more water often reduce the odor within days. Still, a persistent ammonia smell can occasionally point to liver or kidney issues, a urea cycle disorder, or a urinary tract infection rather than diet alone, so the timing and other symptoms matter. There are several important factors to consider, including when this warrants medical attention, so review the complete details below.
If you are unsure whether your body odor is a harmless side effect of your diet or a sign of something that needs attention, guessing can leave you worried or delay care you actually need. A few minutes of structured questions about your diet, hydration, symptoms, and health history can help clarify what is most likely going on and what to do next. Take a free, instant, online symptom check to get personalized insight and clear guidance on your next steps.
Last reviewed for medical accuracy: 09/12/2026
When you switch to a high-protein or ketogenic (keto) diet, you may notice changes in body odor, including an ammonia-like smell in your sweat. Here’s what you need to know about why this happens, when it’s harmless, and when it might signal a deeper issue.
Protein Breakdown & Nitrogen Waste
Keto Diet and Deamination
Hydration Status
Exercise Intensity
An ammonia smell in sweat is generally benign, but in rare cases it may signal:
• Liver or kidney dysfunction
• Urea cycle disorders (genetic conditions impairing ammonia conversion)
• Severe dehydration
• Illnesses that dramatically increase protein breakdown (e.g., certain infections, burns)
If you experience any of the following, seek medical advice:
Balance Your Macronutrients
Stay Well Hydrated
Time Your Protein Intake
Support Your Liver & Kidneys
Shower & Skin Care
Adapt Gradually
If you’re uncertain about your symptoms—or you experience new, worrying signs—you might try a free, online symptom check, using the doctor approved Ubie Symptom Checker. It’s fast, private, and can help you decide whether to seek in-person care.
Ultimately, nothing replaces personalized guidance from a healthcare professional. If you have persistent ammonia odor or any serious symptoms, speak to a doctor. They can:
Speak to a doctor about anything that could be life threatening or serious. If you notice ongoing, strong ammonia smells in your sweat accompanied by other concerning signs—don’t hesitate to get professional help.
Remember: your body’s signals are valuable. Taking them seriously helps you stay healthy and achieve your nutrition goals safely.
(References)
* Watford M, Chellaraj V, Ismat A, Brown P, Raman P. Hepatic glutamine metabolism. Nutrition. 2002 Apr;18(4):301-3. doi: 10.1016/s0899-9007(02)00739-6. PMID: 11934540.
* Chen CM, Lin YS, Wu YR, Chen P, Tsai FJ, Yang CL, Tsao YT, Chang W, Hsieh IS, Chern Y, Soong BW. High Protein Diet and Huntington's Disease. PLoS One. 2015;10(5):e0127654. doi: 10.1371/journal.pone.0127654. Epub 2015 May 19. PMID: 25992839; PMCID: PMC4437787.
* Conway ME, Hutson SM. BCAA Metabolism and NH(3) Homeostasis. Adv Neurobiol. 2016;13:99-132. doi: 10.1007/978-3-319-45096-4_5. PMID: 27885628.
* Holeček M. Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements. Nutr Metab (Lond). 2018;15:33. doi: 10.1186/s12986-018-0271-1. Epub 2018 May 3. PMID: 29755574; PMCID: PMC5934885.
* Cai J, Chen Z, Wu W, Lin Q, Liang Y. High animal protein diet and gut microbiota in human health. Crit Rev Food Sci Nutr. 2022;62(22):6225-6237. doi: 10.1080/10408398.2021.1898336. Epub 2021 Mar 16. PMID: 33724115.
* Epova EY, Shevelev AB, Shurubor YI, Cooper AJL, Biryukova YK, Bogdanova ES, Tyno YY, Lebedeva AA, Krasnikov BF. A novel efficient producer of human ω-amidase (Nit2) in Escherichia coli. Anal Biochem. 2021 Nov 1;632:114332. doi: 10.1016/j.ab.2021.114332. Epub 2021 Aug 12. PMID: 34391728.
* Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods. 2022 Feb;19(2):223-230. doi: 10.1038/s41592-021-01378-y. Epub 2022 Feb 7. PMID: 35132243; PMCID: PMC10926149.
* Sieja KM, Oba PM, Applegate CC, Pendlebury C, Kelly J, Swanson KS. Evaluation of high-protein diets differing in protein source in healthy adult dogs. J Anim Sci. 2023 Jan 3;101. doi: 10.1093/jas/skad057. PMID: 36807528; PMCID: PMC10066725.
* Yoshinari Y, Nishimura T, Yoshii T, Kondo S, Tanimoto H, Kobayashi T, Matsuyama M, Niwa R. A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster. Nat Commun. 2024 Dec 30;15(1):10819. doi: 10.1038/s41467-024-55050-y. Epub 2024 Dec 30. PMID: 39737959; PMCID: PMC11685984.
* Jaschke NP, Luchsinger JR, Chen Z, Wulfmeyer VC, de la Rosa X, Hahn O, Zhang C, Bachtel ND, Cullen JL, Rachner TD, Medzhitov R, Rinschen MM, Wu C, Wang A. Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states. Cell. 2025 Dec 24;188(26):7481-7494.e16. doi: 10.1016/j.cell.2025.10.005. Epub 2025 Nov 4. PMID: 41192423; PMCID: PMC12766652.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.