Our Services
Medical Information
Helpful Resources
Published on: 9/13/2026
Yes, ashwagandha can cause nausea, drowsiness, and a blunted or emotionally flat feeling, especially at higher doses or when first starting it. Stomach upset and nausea are among the most commonly reported side effects, while sedation and mental fogginess may occur because ashwagandha lowers cortisol and calms the nervous system, an effect that can be amplified by sedatives, sleep aids, alcohol, or antidepressants. Rare but serious risks include liver injury and thyroid overactivity, and symptoms like dark urine, yellowing skin, severe abdominal pain, rapid heartbeat, or persistent low mood warrant prompt medical attention rather than watchful waiting. Dose, timing, extract type, duration of use, and underlying thyroid, liver, or mental health conditions all influence whether your symptoms are a harmless adjustment or a signal to stop, so there are several important factors to consider below before you continue or discontinue the supplement.
Because nausea, fatigue, and emotional numbness can also stem from thyroid disorders, depression, anemia, medication interactions, or liver problems that have nothing to do with a supplement, guessing at the cause can delay the right care; a free, instant, online symptom check asks targeted questions about your symptoms, health history, and current medications to help you understand possible explanations and decide whether to adjust your routine, speak with a pharmacist, or see a clinician soon.
Last reviewed for medical accuracy: 09/12/2026
Ashwagandha (Withania somnifera) is a popular herbal supplement often used to help manage stress, support energy levels, and promote overall well-being. While many people tolerate it well, some experience side effects. Below, we explore whether ashwagandha can cause nausea, drowsiness, or feeling emotionally flat, based on credible research and clinical data.
Ashwagandha is classified as an adaptogen—a substance thought to help the body adapt to stress. Its active compounds (withanolides) are believed to:
Most studies find it generally safe, but no supplement is risk-free. Individual responses can vary.
Clinical trials and post-marketing reports highlight a few potential adverse effects. Common issues include:
These side effects are usually mild and resolve on their own within a few days or after adjusting the dose.
Nausea with ashwagandha may stem from:
If nausea persists beyond a week or worsens, consider pausing the supplement and checking your symptoms.
Ashwagandha may promote relaxation and calmness by:
Some users describe a blunting of emotions—feeling neither particularly happy nor sad. This can be unsettling if you’re taking ashwagandha to improve mood or resilience.
While most people tolerate ashwagandha well, certain groups may be more sensitive to its effects:
If you fall into one of these categories, consult your doctor before starting ashwagandha.
Most side effects of ashwagandha are mild and temporary. However, contact a healthcare professional if you experience:
For a free, online symptom check, consider using the doctor-approved Ubie Symptom Checker. It can help you decide whether to seek in-person care.
Ashwagandha can offer benefits such as stress relief, improved sleep, and enhanced resilience. Yet, like any supplement, it may cause side effects in some people, including nausea, mild drowsiness, or a sense of emotional flatness. These reactions tend to be dose-related and often improve with adjustments.
If you experience bothersome or serious symptoms, pause the supplement and speak to a doctor. For non-urgent concerns, you can complete a free, online symptom check using the doctor-approved Ubie Symptom Checker. Always consult a healthcare professional before starting or changing any supplement regimen—especially if you have underlying health conditions or take medications.
Remember: Never ignore symptoms that could be life-threatening or serious. If you experience severe reactions or have concerns, speak to a doctor right away.
(References)
* Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577.
* Sharma AK, Basu I, Singh S. Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial. J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. PMID: 28829155.
* Lewis JE, Poles J, Shaw DP, Karhu E, Khan SA, Lyons AE, Sacco SB, McDaniel HR. The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review. J Clin Transl Res. 2021 Aug 26;7(4):575-620. Epub 2021 Aug 4. PMID: 34541370; PMCID: PMC8445631.
* Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. doi: 10.1371/journal.pone.0257843. Epub 2021 Sep 24. PMID: 34559859; PMCID: PMC8462692.
* Hersant H, He S, Maliha P, Grossberg G. Over the Counter Supplements for Memory: A Review of Available Evidence. CNS Drugs. 2023 Sep;37(9):797-817. doi: 10.1007/s40263-023-01031-6. Epub 2023 Aug 21. PMID: 37603263.
* Della Porta M, Maier JA, Cazzola R. Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review. Nutrients. 2023 Dec 5;15(24). doi: 10.3390/nu15245015. Epub 2023 Dec 5. PMID: 38140274; PMCID: PMC10745833.
* Patibandla S, Gallagher JJ, Patibandla L, Ansari AZ, Qazi S, Brown SF. Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health. Cureus. 2024 Feb;16(2):e55240. doi: 10.7759/cureus.55240. Epub 2024 Feb 29. PMID: 38558676; PMCID: PMC10981444.
* Arumugam V, Vijayakumar V, Balakrishnan A, B Bhandari R, Boopalan D, Ponnurangam R, Sankaralingam Thirupathy V, Kuppusamy M. Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis. Explore (NY). 2024 Nov-Dec;20(6):103062. doi: 10.1016/j.explore.2024.103062. Epub 2024 Sep 21. PMID: 39348746.
* Ahmed A, Alali AM, Abdullah E, Alharbi MN, Alayoubi HM. Herbal Remedies for Hair Loss: A Review of Efficacy and Safety. Skin Appendage Disord. 2025 Aug;11(4):360-371. doi: 10.1159/000542876. Epub 2025 Jan 20. PMID: 40771449; PMCID: PMC12324729.
* Kumar A, Sah BK, Ahmad F, Jamwal V, Sahu SK. Potential Adverse Effects of Ashwagandha: A Critical Review of Preclinical and Clinical Evidence. Phytother Res. 2026 Aug;40(8):4913-4931. doi: 10.1002/ptr.70158. Epub 2026 Jan 8. PMID: 41502355; PMCID: PMC13436050.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.