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Published on: 7/22/2025

What's Causing My Chronic Abdominal Pain Despite Negative Tests?

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50s, Female

I have undergone several tests, including a colonoscopy, endoscopy, two abdominal ultrasounds, and one vaginal ultrasound, but nothing has been found to explain my pain. The pain is limiting my exercise, which is now impacting my ability to manage my type two diabetes. I have intentionally lost 35 pounds and am currently at a healthy weight. Despite seeing a doctor, I have not received a diagnosis. What might be causing my current symptoms?

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Dr. Taylor’s Response

I understand your frustration with ongoing lower abdominal pain, especially given its impact on your diabetes management. It's commendable that you've lost weight and are working hard to stay healthy.

In my experience, unexplained abdominal pain, even after extensive testing, can sometimes be related to:

  • Musculoskeletal issues (like abdominal wall strain)
  • Nerve irritation or entrapment
  • Pelvic floor dysfunction
  • Chronic pain syndromes
  • Small intestinal bacterial overgrowth (SIBO)

Given the impact on your diabetes management, I strongly recommend discussing this with your primary care doctor or endocrinologist. They might consider:

  • Referral to a pain specialist or neurologist
  • Physical therapy evaluation
  • Alternative exercise options (like swimming or seated exercises)
  • Further metabolic testing related to your diabetes

Remember, managing chronic conditions often requires a team approach. Don't hesitate to advocate for yourself and express your concerns about how this pain is affecting your overall health.

Keep up the great work with your weight management. Stay positive and continue working closely with your healthcare team to find a solution that allows you to exercise comfortably and manage your diabetes effectively.

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