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Published on: 11/13/2025

What causes narcolepsy, and how do "sleep attacks" happen?

Narcolepsy is a sleep disorder that may be caused by the immune system attacking certain brain cells, leading to sudden 'sleep attacks'.

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Explanation

Narcolepsy is a condition where people suddenly fall asleep during the day. This happens because the brain has trouble controlling sleep and wakefulness. One reason for narcolepsy is that the immune system might mistakenly attack parts of the brain that help us stay awake.

Causes of Narcolepsy:

  • Immune System Attack: Research suggests that narcolepsy, especially Type 1, may occur when the immune system attacks brain cells that produce a chemical called hypocretin, which helps keep us awake.
  • Autoantibodies: Some studies have found that certain antibodies (proteins in the blood that fight infections) might target brain cells, contributing to narcolepsy.

How 'Sleep Attacks' Happen:

  • Sudden Sleepiness: When the brain doesn't have enough hypocretin, it can cause sudden and uncontrollable episodes of sleep, known as 'sleep attacks'.
  • Brain Cell Damage: Damage to specific brain cells disrupts normal sleep patterns, making it hard for people to stay awake during the day.

Understanding narcolepsy is important for finding better treatments and helping people manage their symptoms.

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