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Published on: 12/11/2025
CDC recommends isolating for at least 5 days after symptom onset or a positive test (Day 0 is the day symptoms start/test), ending after day 5 only if you’ve been fever-free for 24 hours and symptoms are improving; keep masking around others through day 10 (asymptomatic isolate 5 days; severe illness or weakened immunity may need 10+ days). There are several factors to consider—who needs to isolate (including some close contacts), optional test-based clearance, avoiding high‑risk settings until day 11, and what to do if symptoms return—see below for important details that could change your next steps.
Staying up to date on isolation guidelines helps protect you and others from spreading COVID-19. Below is an overview of the Centers for Disease Control and Prevention’s (CDC) current recommendations for isolating after a positive test or known exposure. Always look out for serious symptoms and speak to a doctor if you’re ever concerned about your health.
These recommendations apply if you have symptoms but aren’t severely sick or immunocompromised.
If you never develop symptoms:
If you were hospitalized, had severe illness, or have a weakened immune system:
Even after isolation ends, continue to protect others:
The CDC no longer requires negative tests to end isolation for most people. However, if you choose a test‐based strategy:
Contact a healthcare provider or call 911 if you experience any of the following:
If you have any serious or life‐threatening concerns, speak to a doctor right away.
Not sure if you have COVID-19 or need further guidance? Consider doing a free, online symptom check for COVID-19 to help decide your next steps.
By following these CDC guidelines—isolating at least 5 days, masking through day 10, and monitoring your health—you help protect your community and yourself. Stay informed, stay safe, and always reach out to a medical professional if you have serious symptoms or questions about your health.
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