Things Not to Do While on Chemotherapy

Chemotherapy is a powerful cancer treatment that attacks rapidly dividing cells. While it can be life-saving, it also affects healthy cells and can cause side effects that range from mild to severe. Being mindful of activities, foods, and behaviors you should avoid can help you tolerate treatment better, reduce complications, and maintain quality of life.

Below you’ll find evidence-based guidance on things not to do while on chemotherapy. Always speak with your oncology team before making changes to your routine.

1. Don’t Ignore Infection Risks

Chemotherapy often lowers your white blood cell count (neutropenia), making infections more dangerous.

• Avoid crowded places and close contact with anyone who is sick (colds, flu, or other infections).
• Don’t skip frequent handwashing with soap and water or alcohol-based sanitizer.
• Avoid raw or undercooked foods (e.g., sushi, rare meat, unpasteurized dairy) that can carry bacteria or parasites.
• Don’t neglect dental care—gum infections can spread quickly. Brush gently and see your dentist if you notice swelling or bleeding.

2. Don’t Overlook Proper Nutrition

Good nutrition supports healing, strength, and energy levels. Chemotherapy can cause taste changes, nausea, or mouth sores, making it tempting to skip meals or reach for unhealthy comfort foods.

• Avoid high-fat, fried, or overly spicy foods if they trigger nausea.
• Don’t rely on sugary snacks and sodas—empty calories can worsen fatigue and blood sugar swings.
• Steer clear of foods that upset your stomach (e.g., citrus if you have mouth sores).
• Avoid restrictive diets unless approved by your oncology dietitian; you need calories, protein, and nutrients.

3. Don’t Push Through Extreme Fatigue

Fatigue is one of the most common side effects of chemotherapy. Ignoring your body’s need for rest may worsen the problem.

• Don’t stick to your pre-treatment schedule if you feel exhausted.
• Avoid working long hours or doing heavy chores on “bad” days.
• Don’t skip planned naps or breaks—short rests can improve energy levels.
• Avoid isolation—low-impact social activities (short walks, gentle stretches, video calls) can boost mood without overtaxing your energy.

4. Don’t Take Non-Approved Supplements or Herbal Remedies

Many supplements can interfere with chemotherapy drugs, altering how they work or increasing side effects.

• Don’t assume “natural” equals safe—St. John’s wort, for example, can reduce chemotherapy effectiveness.
• Avoid high-dose vitamins (such as Vitamin E) without discussing with your oncologist.
• Don’t start new herbal teas or remedies without approval from your medical team.
• Stick to medications and supplements your care team has reviewed.

5. Don’t Skip or Alter Medications Without Guidance

Chemotherapy schedules are carefully calibrated. Skipping doses or changing timing can reduce effectiveness or raise toxicity.

• Don’t stop anti-nausea or pain medications on your own if they cause side effects—talk to your doctor about adjustments.
• Avoid self-medicating with over-the-counter pain relievers (NSAIDs like ibuprofen) unless cleared by your oncologist. They can increase bleeding risk, especially if your platelets are low.
• Don’t share prescription drugs with family or friends.

6. Don’t Neglect Skin and Mouth Care

Skin rashes and mouth sores are common during chemo. Ignoring these can lead to infection and discomfort.

• Avoid harsh soaps, fragrances, and hot water when bathing—use gentle, fragrance-free cleansers.
• Don’t pick at dry skin or blisters; apply recommended moisturizers liberally.
• Avoid alcohol-based mouthwashes if you have mucositis (mouth sores).
• Don’t eat hard, crunchy, or acidic foods if you have mouth irritation—opt for soft, bland foods.

7. Don’t Expose Yourself to Harmful Radiation

Some imaging studies involve radiation; your oncology team will advise timing relative to chemo cycles.

• Don’t schedule non-urgent X-rays or CT scans without checking with your care team.
• Avoid prolonged sun exposure—chemotherapy can make your skin more sensitive. Use broad-spectrum sunscreen (SPF 30+) and protective clothing.
• Don’t use tanning beds or sunlamps.

8. Don’t Ignore Mental Health and Emotional Needs

Chemotherapy can trigger anxiety, depression, and stress. Neglecting emotional well-being can affect your physical health.

• Don’t isolate yourself—connect with family, friends, or support groups (in person or online).
• Avoid bottling up feelings; consider counseling or therapy as recommended by your care team.
• Don’t rely solely on willpower—mind-body practices like guided meditation, gentle yoga, or breathing exercises can help.

9. Don’t Engage in High-Risk Physical Activities

Your risk of bleeding and infection can increase if platelets and white blood cells are low.

• Avoid contact sports (e.g., football, soccer) or activities with a high fall risk (e.g., downhill skiing).
• Don’t lift very heavy weights or perform strenuous exercises without a physical therapist’s approval.
• Avoid hot tubs and public swimming pools during periods of low immunity.

10. Don’t Miss Symptom Monitoring

Early reporting of side effects helps your care team manage and adjust treatment.

• Don’t delay reporting fever, chills, severe nausea, vomiting, diarrhea, or bleeding.
• Avoid underestimating new symptoms—what seems minor can become serious quickly.
• Consider a free, online symptom check, using the doctor approved Ubie Symptom Checker, to track and share your symptoms with your care team.

Final Thoughts

Chemotherapy demands vigilance, self-care, and close communication with your medical team. While it’s essential to avoid the behaviors above, remember that each person’s treatment plan and side effects are unique. Always:

• Keep an open line with your oncologist, nurse, and pharmacist
• Follow their instructions on diet, activity level, and medication
• Speak up promptly about any new or worsening symptom

This guidance is meant to help you navigate treatment safely but does not replace personalized medical advice. If you experience severe pain, uncontrolled bleeding, high fever, or any life-threatening symptom, speak to a doctor immediately.