Which treatments are most effective for cystic acne in patients with PCOS?

Cystic acne is a severe form of acne that can be challenging to treat, especially in patients with PCOS. According to the studies provided, isotretinoin, also known as 13-cis-retinoic acid, is a very effective treatment for severe cystic acne.

1. Effectiveness of Isotretinoin:

• The studies show that isotretinoin significantly reduces severe acne compared to a placebo. This medication works by reducing the size of the oil glands in the skin, which decreases oil production and helps prevent clogged pores.

2. Study Highlights:

• One study compared isotretinoin to a placebo and found a significant improvement in acne symptoms for those taking isotretinoin.
• Another study focused on severe cystic acne and demonstrated the effectiveness of isotretinoin in reducing acne lesions.

In conclusion, isotretinoin is a strong option for treating cystic acne and has been shown to be effective in the studies referenced. However, it's important to consult with a healthcare provider for personalized medical advice and to discuss potential side effects and monitoring during treatment.