Published on: 3/17/2025
Yes, there can be a relationship between diarrhea and testicle pain in certain cases.
Testicle pain and diarrhea can be linked, though not commonly. In fact, the anatomical proximity between the digestive and reproductive systems can sometimes lead to shared symptoms or complications. The spread of infection through lymphatic channels or blood vessels can affect multiple organ systems simultaneously. Understanding this connection helps explain why gastrointestinal infections might manifest with seemingly unrelated symptoms like testicular discomfort. As an example, Salmonella, which typically causes diarrhea, can also lead to epididymo-orchitis - an inflammatory condition affecting the testicles and epididymis. Hernias can also cause both diarrhea and testicle pain because when intestinal tissue pushes through a weak spot in the abdominal wall near the groin (inguinal hernia), it can compress both the intestinal tract and spermatic cord, leading to digestive issues and testicular discomfort simultaneously. Additionally, certain autoimmune conditions like inflammatory bowel disease (IBD) can cause both digestive symptoms and symptoms affecting the genitourinary system. It's important to consult a healthcare provider for proper diagnosis and treatment if you are experiencing both symptoms simultaneously.
(References)
Sanagawa M, Kenzaka T, Kato S, Yamaoka I, Fujimoto S. _Campylobacter jejuni_ enterocolitis presenting with testicular pain: A case report. World J Clin Cases. 2020 Aug 6;8(15):3280-3283. doi: 10.12998/wjcc.v8.i15.3280. PMID: 32874982; PMCID: PMC7441251.
Mahmoud MAM, Megahed G, Yousef MS, Ali FAZ, Zaki RS, Abdelhafeez HH. _Salmonella_ Typhimurium Triggered Unilateral Epididymo-Orchitis and Splenomegaly in a Holstein Bull in Assiut, Egypt: A Case Report. Pathogens. 2020 Apr 24;9(4):314. doi: 10.3390/pathogens9040314. PMID: 32344573; PMCID: PMC7238186.
Shehzad KN, Riaz AA. Unusual cause of a painful right testicle in a 16-year-old man: a case report. J Med Case Rep. 2011 Jan 21;5:27. doi: 10.1186/1752-1947-5-27. PMID: 21255387; PMCID: PMC3032707.
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