Our Services
Medical Information
Helpful Resources
Published on: 8/20/2026
Certain medications can impair memory and cognitive function. The most common culprits include benzodiazepines (such as diazepam and lorazepam), anticholinergic drugs (found in some allergy, bladder, and sleep medications), opioid pain relievers, and specific antidepressants. These drugs may cause short-term forgetfulness, difficulty concentrating, or, in some cases, longer-lasting memory issues, particularly in older adults.
If you're experiencing memory problems and aren't sure whether your medication, an underlying condition, or another factor is to blame, it's worth investigating sooner rather than later. Memory changes can have many causes, and identifying the right one is the first step toward feeling like yourself again. Take a free, instant, online symptom check to get personalized insights into what may be causing your symptoms and clear guidance on your next steps.
Reviewed for medical accuracy: 07/15/2026
Quick answers
The most common questions people search after this page
Some medicines that affect the brain can make it harder to remember things. For example, benzodiazepines are a type of sedative used to help with anxiety or sleep, but they may slow down brain signals and affect memory. Drugs with anticholinergic properties, which are found in some allergy medicines, bladder relaxants, and even some antidepressants, can also block important brain chemicals needed for memory. Opioids, which are used for pain, might change how the brain works too.
Additionally, certain antidepressants and antipsychotics have been noted to impact memory, especially when used in higher doses or for longer times. In patients with kidney problems, like those described in recent studies, these drugs might stay in the body longer and have a bigger effect on memory.
It is important to remember that individual reactions can vary, and if someone notices memory problems while taking these medicines, they should speak with a doctor to see if another option could work better. If you're experiencing concerning symptoms related to your medications, you can check your symptoms to better understand what might be happening and prepare for your conversation with your healthcare provider.
(References)
Hafez G, Malyszko J, Golenia A, Klimkowicz-Mrowiec A, Ferreira AC, Arıcı M, Bruchfeld A, Nitsch D, Massy ZA, Pépin M, Capasso G, Mani LY, Liabeuf S; CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target). Drugs with a negative impact on cognitive functions (Part 2): drug classes to consider while prescribing in CKD patients. Clin Kidney J. 2023 Sep 18;16(12):2378-2392. doi: 10.1093/ckj/sfad239. PMID: 38046029; PMCID: PMC10689198.
Shinohara M, Yamada M. [Drug-induced Cognitive Impairment]. Brain Nerve. 2016 Apr;68(4):421-8. Japanese. doi: 10.11477/mf.1416200415. PMID: 27056860.
Chavant F, Favrelière S, Lafay-Chebassier C, Plazanet C, Pérault-Pochat MC. Memory disorders associated with consumption of drugs: updating through a case/noncase study in the French PharmacoVigilance Database. Br J Clin Pharmacol. 2011 Dec;72(6):898-904. doi: 10.1111/j.1365-2125.2011.04009.x. PMID: 21557759; PMCID: PMC3244635.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.