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Published on: 3/5/2025

Does Epilepsy Cause Memory Loss?

Epilepsy can sometimes affect memory, especially long-term memory, with problems related to the location of the seizures and the age when epilepsy started.

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Explanation

Epilepsy is a brain condition where people have seizures. When seizures come from a part of the brain called the temporal lobe, which is very important for keeping our memories, this may result in difficulty with remembering things. Studies show that some people with epilepsy may have problems with long-term memory, meaning they might find it hard to remember what happened long ago. It is also seen that if a person's epilepsy starts at a young age, the memory difficulties might appear differently than if it starts later in life. With early onset, the way the brain develops and stores memories can be affected over many years. Not everyone with epilepsy will have problems with memory, and the impact can vary from person to person. Doctors often look at where the seizures occur in the brain and when they started in order to better understand the memory challenges. Treatments and support can also make a difference in helping people manage memory problems and lead better lives.

(References)

  • Tramoni-Negre E, Lambert I, Bartolomei F, Felician O. Long-term memory deficits in temporal lobe epilepsy. Rev Neurol (Paris). 2017 Jul-Aug;173(7-8):490-497. doi: 10.1016/j.neurol.2017.06.011. Epub 2017 Aug 31. PMID: 28838789.

  • Rayner G, Jackson GD, Wilson SJ. Mechanisms of memory impairment in epilepsy depend on age at disease onset. Neurology. 2016 Oct 18;87(16):1642-1649. doi: 10.1212/WNL.0000000000003231. Epub 2016 Sep 16. PMID: 27638925; PMCID: PMC5085077.

  • Höller Y, Michaelis R, Trinka E, Jacobs J. Editorial: Effects of epilepsy on memory-Therapeutic implications, biomarkers, and comorbidities. Front Neurol. 2023 Feb 9;14:1140941. doi: 10.3389/fneur.2023.1140941. PMID: 36846151; PMCID: PMC9948013.

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