Our Services
Medical Information
Helpful Resources
Published on: 9/23/2026
Hemoglobin is the iron-rich protein inside red blood cells that binds oxygen in the lungs, carries it to every tissue and organ, and helps transport carbon dioxide back out to be exhaled. It also helps maintain healthy blood pH and gives blood its red color, so levels that are too low (anemia) or too high can cause fatigue, shortness of breath, dizziness, headaches, or pale skin. Several factors influence your levels, including iron and vitamin intake, hydration, altitude, pregnancy, smoking, kidney health, and inherited conditions like sickle cell disease or thalassemia, so see below for the important details behind the numbers.
Because symptoms of abnormal hemoglobin overlap with many other conditions, it helps to organize what you are feeling before assuming it is "just tiredness." Take a free, instant, online symptom check to see which possible causes match your symptoms and get clear guidance on what to do next.
Last reviewed for medical accuracy: 09/23/2025
Hemoglobin is a protein in red blood cells that plays a vital role in your overall health. Understanding what hemoglobin does can help you recognize signs of imbalance and take action before small issues become serious.
Hemoglobin is responsible for carrying gases between your lungs and the rest of your body. Without it, tissues wouldn’t get the oxygen they need to function properly.
Oxygen Transport
Carbon Dioxide Removal
Acid-Base Balance
Nitric Oxide Transport
Your hemoglobin concentration is measured in grams per deciliter (g/dL). Normal ranges vary slightly by age and sex:
Levels outside these ranges can signal an underlying health issue:
Anemia occurs when your hemoglobin is below the normal range. Common causes include:
Polycythemia is when hemoglobin levels are abnormally high. It can be:
A routine complete blood count (CBC) measures hemoglobin along with other blood components. Your doctor may also order:
If you experience any of the following, consider a free, online symptom check, using the doctor approved Ubie Symptom Checker, and then speak to a doctor:
A quick online check can guide you on the next steps, but it’s not a substitute for professional care. Always contact your healthcare provider if you believe you may have a serious condition.
Hemoglobin is essential for oxygen delivery, carbon dioxide removal, and maintaining a healthy blood pH. Understanding what does hemoglobin do helps you recognize symptoms of imbalance and take steps to correct them. If you suspect your hemoglobin levels are off, try a free, online symptom check, using the doctor approved Ubie Symptom Checker, and be sure to speak to a doctor about any concerns that could be life-threatening or serious. Taking action early can help you maintain energy, vitality and overall well-being.
(References)
* Hercberg S, Rouaud C. Nutritional anaemia. Child Trop. 1981;(133):1-36. PMID: 12264581.
* JONXIS JH. [HEMOGLOBINOPATHY]. Folia Med Neerl. 1964 May;7:62-81. PMID: 14153453.
* Blankenburg M, Kraemer N, Hirschfeld G, Krumova EK, Maier C, Hechler T, Aksu F, Magerl W, Reinehr T, Wiesel T, Zernikow B. Childhood diabetic neuropathy: functional impairment and non-invasive screening assessment. Diabet Med. 2012 Nov;29(11):1425-32. doi: 10.1111/j.1464-5491.2012.03685.x. PMID: 22507184.
* Jones MR, Robbins BW, Augustine M, Doyle J, Mack-Fogg J, Jones H, White PH. TRANSFER FROM PEDIATRIC TO ADULT ENDOCRINOLOGY. Endocr Pract. 2017 Jul;23(7):822-830. doi: 10.4158/EP171753.OR. Epub 2017 May 23. PMID: 28534683.
* Dixon RF, Zisser H, Layne JE, Barleen NA, Miller DP, Moloney DP, Majithia AR, Gabbay RA, Riff J. A Virtual Type 2 Diabetes Clinic Using Continuous Glucose Monitoring and Endocrinology Visits. J Diabetes Sci Technol. 2020 Sep;14(5):908-911. doi: 10.1177/1932296819888662. Epub 2019 Nov 25. PMID: 31762302; PMCID: PMC7477772.
* Aiello LP, Cavallerano J, Sun J, Salti N, Nasrallah M, Mehanna CJ, El Salloukh NA, Salti HI. Long-Term Effect on HbA1c in Poorly Controlled Diabetic Patients Following Nonmydriatic Retinal Image Review at the Time of Endocrinology Visit. Telemed J E Health. 2020 Oct;26(10):1265-1270. doi: 10.1089/tmj.2019.0239. Epub 2020 Jan 14. PMID: 31934834.
* Slåtsve KB, Claudi T, Lappegård KT, Jenum AK, Larsen M, Nøkleby K, Cooper JG, Sandberg S, Berg TJ. Factors associated with treatment in primary versus specialist care: A population-based study of people with type 2 and type 1 diabetes. Diabet Med. 2021 Jul;38(7):e14580. doi: 10.1111/dme.14580. Epub 2021 May 5. PMID: 33834523.
* Coates CJ, Belato FA, Halanych KM, Costa-Paiva EM. Structure-Function Relationships of Oxygen Transport Proteins in Marine Invertebrates Enduring Higher Temperatures and Deoxygenation. Biol Bull. 2022 Oct;243(2):134-148. doi: 10.1086/722472. Epub 2022 Nov 11. PMID: 36548976.
* Ramsook AH, Dominelli PB, Angus SA, Senefeld JW, Wiggins CC, Joyner MJ. The oxygen transport cascade and exercise: Lessons from comparative physiology. Comp Biochem Physiol A Mol Integr Physiol. 2023 Aug;282:111442. doi: 10.1016/j.cbpa.2023.111442. Epub 2023 May 13. PMID: 37182787; PMCID: PMC10330610.
* Lado-Abeal J, Gude F, Ginzo-Villamayor MJ, Al-Zubaidi K, Stocking JC, Rodriguez-Carnero G, Guo A, Surampudi P, Lenaerts C, Babu VK, Plante D, Huang Y, Fernandez-Pombo A. Impact of specialised endocrinology care on metabolic control and healthcare utilisation outcomes after kidney transplantation in patients with diabetes: A 12-month observational cohort study. Diabetes Obes Metab. 2026 May;28(5):4082-4090. doi: 10.1111/dom.70596. Epub 2026 Feb 23. PMID: 41725429; PMCID: PMC13071252.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.