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Published on: 9/26/2026

What are the side effects of kava?

Kava is most often linked to drowsiness, headache, dizziness, stomach upset, and, with heavy or prolonged use, a dry scaly rash known as kava dermopathy. More serious concerns include liver injury such as hepatitis and liver failure, impaired coordination and driving ability, and risky interactions with alcohol, sedatives, and antidepressants. Your personal risk depends on several factors, including dose, how long you use it, the type of extract, and any existing liver problems, so see below to understand the important details before continuing or stopping use.

Because symptoms like fatigue, nausea, dark urine, or yellowing skin can signal something more urgent than a mild reaction, it helps to get a structured read on what your body is telling you. Take a free, instant, online symptom check to better understand your symptoms and decide whether self-care, a pharmacist visit, or prompt medical attention is your best next step.

Last reviewed for medical accuracy: 09/26/2026

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Explanation

Kava Side Effects

Kava, a plant native to the South Pacific, has gained popularity worldwide for its calming and anxiety-relieving properties. While many people use kava to unwind, it’s important to understand its potential side effects. This guide draws on credible sources such as the U.S. National Institutes of Health (NIH) and the Mayo Clinic to give you a clear, balanced view.

How Kava Works

Kava contains compounds called kavalactones, which are thought to interact with brain receptors involved in mood regulation. By affecting GABA (gamma-aminobutyric acid) pathways, kava can produce feelings of relaxation and mild sedation. However, these same effects can also lead to unwanted reactions in some individuals.


Common Side Effects

Most people tolerate kava well when used at recommended doses. Still, some experience mild to moderate side effects:

  • Gastrointestinal upset
    • Nausea or stomach discomfort
    • Occasional diarrhea
  • Central nervous system effects
    • Drowsiness or sedation
    • Headache or lightheadedness
  • Mouth and throat sensations
    • A tingling or numb feeling in the mouth
    • Dry mouth
  • Skin changes (with prolonged use)
    • Mild rash or itching

These effects are usually reversible once kava intake is stopped or reduced. Drinking plenty of water and avoiding heavy machinery or driving while drowsy can help manage these symptoms.


Serious (But Rare) Side Effects

While rare, certain side effects can be severe. You should seek medical advice if you notice any of the following:

  • Liver toxicity
    • Symptoms: jaundice (yellowing of skin or eyes), dark urine, severe abdominal pain
  • Allergic reactions
    • Symptoms: hives, difficulty breathing, facial swelling
  • Severe skin changes (kava dermopathy)
    • Thickening, scaling, or dry, flaky skin after months of heavy use
  • Neurological issues
    • Confusion, hallucinations, or severe muscle weakness

If you experience any signs of liver injury or severe allergic reaction, stop using kava immediately and consult a healthcare provider.


Who Should Avoid Kava

Kava may not be suitable for everyone. Avoid kava if you:

  • Have a history of liver disease or elevated liver enzymes
  • Are pregnant or breastfeeding
  • Take medications that affect the liver (e.g., acetaminophen, statins)
  • Use drugs that depress the central nervous system (e.g., benzodiazepines, opioids)
  • Consume large amounts of alcohol regularly
  • Have Parkinson’s disease or are on levodopa treatment

Drug and Herbal Interactions

Kava can interact with a range of medications and supplements. Always check with your doctor or pharmacist before combining kava with:

  • Sedatives and sleep aids (e.g., benzodiazepines, barbiturates)
  • Antidepressants (risk of excessive sedation or serotonin imbalance)
  • Antiepileptic drugs (possible increased neurotoxicity)
  • Alcohol (adds to sedation and liver burden)
  • Other herbal supplements that affect liver enzymes (e.g., St. John’s wort, valerian)

Combining kava with these substances can amplify side effects such as drowsiness, dizziness, or liver damage.


Tips for Safer Kava Use

If you decide to try kava, consider these best practices:

  • Choose reputable products
    • Look for standardized extracts listing total kavalactone content
    • Avoid products with stems or leaves (higher risk of liver toxicity)
  • Start with low doses
    • Follow label instructions or professional guidance
    • Monitor your body’s response before increasing the amount
  • Limit frequency and duration
    • Use kava for short periods (no more than a few weeks at a time)
    • Take breaks to give your liver a rest
  • Stay hydrated and well-nourished
    • Drink water alongside kava to support digestion and overall health
  • Monitor your health
    • Keep an eye on any unusual symptoms
    • Consider periodic liver-function tests if you use kava regularly

When to Seek Help

Even mild side effects can worsen if overlooked. If you notice troubling symptoms—especially those affecting your liver or breathing—don’t wait. You might also consider a free, online symptom check, using the doctor approved Ubie Symptom Checker. This tool can help you gauge whether you need immediate medical attention or a follow-up with a healthcare provider.


Key Takeaways

  • Most kava side effects are mild: drowsiness, GI upset, or tingling sensation in the mouth.
  • Serious reactions (liver toxicity, allergic response) are rare but require prompt medical attention.
  • Avoid kava if you have liver issues, take certain medications, or drink heavily.
  • Always start with low doses and reputable products, and limit long-term use.
  • For any worrying symptoms, pause kava use and speak to a doctor right away.

This information is for educational purposes and does not replace professional medical advice. Always speak to a qualified healthcare provider about any life-threatening or serious concerns related to kava or other supplements.

(References)

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  • * Maddrey WC. Drug-induced hepatotoxicity: 2005. J Clin Gastroenterol. 2005 Apr;39(4 Suppl 2):S83-9. doi: 10.1097/01.mcg.0000155548.91524.6e. PMID: 15758665.

  • * Teschke R, Sarris J, Schweitzer I. Kava hepatotoxicity in traditional and modern use: the presumed Pacific kava paradox hypothesis revisited. Br J Clin Pharmacol. 2012 Feb;73(2):170-4. doi: 10.1111/j.1365-2125.2011.04070.x. PMID: 21801196; PMCID: PMC3269575.

  • * Abenavoli L, Libri E, Bosco D, Gallo D, Luzza F. [Drug-induced liver injury]. Recenti Prog Med. 2012 Feb;103(2):79-84. doi: 10.1701/1045.11392. PMID: 22430754.

  • * Posadzki P, Watson LK, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med (Lond). 2013 Feb;13(1):7-12. doi: 10.7861/clinmedicine.13-1-7. PMID: 23472485; PMCID: PMC5873713.

  • * Raziq FI. Kava Kava Induced Acute Liver Failure. Am J Ther. 2022 Jul 1;29(4):493-494. doi: 10.1097/MJT.0000000000001180. Epub 2022 Jul 1. PMID: 32467497.

  • * Schmidt M, Thomsen M, Kuchta K. Kava Kava-Associated Acute Liver Failure? Am J Ther. 2022 Nov-Dec 01;29(6):e729-e731. doi: 10.1097/MJT.0000000000001240. Epub 2020 Dec 29. PMID: 33416242.

  • * Drugs for anxiety disorders. Med Lett Drugs Ther. 2023 Aug 7;65(1682):121-128. doi: 10.58347/tml.2023.1682a. PMID: 37516898.

  • * Yeom JW, Cho CH. Herbal and Natural Supplements for Improving Sleep: A Literature Review. Psychiatry Investig. 2024 Aug;21(8):810-821. doi: 10.30773/pi.2024.0121. Epub 2024 Aug 2. PMID: 39086164; PMCID: PMC11321869.

  • * Brotherton K, Chacko B. Case Report: Something Is Brewing. Nephrology (Carlton). 2025 May;30(5):e70051. doi: 10.1111/nep.70051. PMID: 40343400; PMCID: PMC12059527.

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