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Published on: 4/28/2025

What Could Be the Underlying Issues If I Experience Problems Only on the Left Side of My Body?

Problems only on one side of your body can come from a variety of issues like nerve or brain problems (for example, a stroke), heart-related pain, kidney issues, or even rare conditions affecting organs on that side.

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Explanation

When you experience symptoms only on one side, several underlying issues may be responsible. One possibility is a neurological event, like a stroke, that affects one side of the brain and leads to weakness or numbness only on one side. Another potential cause is a heart issue. The heart is mostly on the left side of your body, so problems such as angina or a heart attack can lead to pain or discomfort there. One-sided flank pain might not always be caused by kidney stones; sometimes other kidney or vascular issues are at play. In addition, problems in the upper abdomen on the left side could be due to conditions affecting organs like the spleen or stomach, though these are less common. Because these issues can be serious, it’s important to get a thorough medical evaluation. A healthcare provider will ask about your symptoms, perform a physical exam, and may order blood tests or imaging studies to determine the exact cause and guide treatment.

(References)

  • Schneider R, Gautier JC. Leg weakness due to stroke. Site of lesions, weakness patterns and causes. Brain. 1994 Apr;117 ( Pt 2):347-54. doi: 10.1093/brain/117.2.347. PMID: 8186960.

  • Foreman RD, Garrett KM, Blair RW. Mechanisms of cardiac pain. Compr Physiol. 2015 Apr;5(2):929-60. doi: 10.1002/cphy.c140032. PMID: 25880519.

  • Feit L, John D, Delgado Torres N, Sinert R. Flank pain and hematuria is not always a kidney stone. Am J Emerg Med. 2021 Feb;40:225.e1-225.e2. doi: 10.1016/j.ajem.2020.07.046. Epub 2020 Jul 24. PMID: 32958382.

  • Aiyegbeni B, Jonnalagadda S, Creedon L, Teibe A. Rare Cause of Left Upper Abdominal Pain. Prague Med Rep. 2021;122(2):106-111. doi: 10.14712/23362936.2021.11. PMID: 34137686.

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