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Published on: 11/7/2025
Can I take omeprazole long-term?
Long-term use of omeprazole can be safe for some people, but it may come with risks. It's important to talk to a doctor about your specific situation. See below to understand more.
Questions about your long-term omeprazole use?
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Omeprazole is a type of medicine called a proton pump inhibitor (PPI). It helps reduce stomach acid. Some people take it for a long time to help with things like acid reflux or ulcers.
Safety of Long-term Use
- According to research, omeprazole can be safe for long-term use in many people. However, it may cause changes in the stomach lining.
- Another study suggests there might be risks, such as a higher chance of certain health problems. These could include bone fractures or kidney issues.
Considerations
- If you need to take omeprazole for a long time, it's important to have regular check-ups with your doctor.
- Your doctor can help decide if it's right for you and discuss any possible risks.
Always talk to your doctor before making any changes to how you take your medicine. They can help you understand what's best for your health.
(References)
- Klinkenberg-Knol EC, Nelis F, Dent J, Snel P, Mitchell B, Prichard P, et al. (2000). efficacy, safety, and influence on gastric mucosa. Gastroenterology, 10734017.
- Koyyada A. (2021). Long-term use of proton pump inhibitors as a risk factor for .... Therapie, 32718584.
- Attwood SE, Ell C, Galmiche JP, Fiocca R, Hatlebakk JG, Hasselgren B, et al. (2015). Long-term safety of proton pump inhibitor therapy .... Alimentary pharmacology & therapeutics, 25858519.
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