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Published on: 9/24/2026
A common starting point for women over 40 is roughly 30 to 35% protein, 30 to 35% carbohydrates, and 25 to 30% fat, with protein intake near 1.2 to 1.6 grams per kilogram of body weight to protect muscle mass during perimenopause and menopause. Higher protein and fiber-rich carbs help offset declining estrogen, slower metabolism, insulin resistance, and bone loss, while healthy fats support hormone production. Activity level, body composition goals, thyroid or blood sugar conditions, and training intensity all shift the ideal ratio, so there are several important factors to weigh before locking in numbers. See below for the full breakdown, sample daily targets, and adjustments for weight loss versus muscle gain.
If fatigue, stubborn weight changes, bloating, or irregular cycles are part of why you are rethinking your macros, nutrition may only be part of the picture, since thyroid issues, insulin resistance, anemia, and perimenopausal hormone shifts can all produce similar symptoms and change what your body actually needs. A free, instant, online symptom check can help you sort out which of your symptoms are expected midlife changes and which deserve a conversation with a clinician, so you can act on real answers instead of guessing.
Last reviewed for medical accuracy: 09/24/2026
What Are Macros?
“Macros” is short for macronutrients—the nutrients your body needs in larger amounts to function, grow, and repair. The three primary macronutrients are:
Understanding what are macros—and how to balance them—can be especially important for women over 40, when changes in hormones, metabolism, and lifestyle often affect body composition and energy levels.
As women enter their 40s and beyond, natural declines in estrogen, shifts in body composition, and possible reductions in activity can lead to:
An appropriate macro split helps you:
While individual needs vary based on genetics, activity level, health status, and goals, credible guidelines (such as those from the Academy of Nutrition and Dietetics and the American Heart Association) suggest the following starting points:
| Macronutrient | Percentage of Total Calories | Notes |
|---|---|---|
| Protein | 25% – 30% | Aim for 1.0–1.2 grams per kilogram of body weight to maintain muscle. |
| Fats | 25% – 35% | Focus on unsaturated fats (olive oil, nuts, seeds, fatty fish). |
| Carbohydrates | 35% – 45% | Prioritize fiber-rich whole grains, vegetables, and fruits. |
Higher Protein (25–30%):
• Counters age-related muscle loss (sarcopenia).
• Boosts metabolism via the thermic effect of food (protein takes more energy to digest).
• Supports mood and hormone production.
Moderate Carbs (35–45%):
• Provides energy for daily activities and exercise.
• Emphasis on fiber-rich carbs helps control blood sugar and supports gut health.
Healthy Fats (25–35%):
• Essential for estrogen and other hormone synthesis.
• Enhances nutrient absorption (vitamins A, D, E, K).
• Increases satiety and supports heart health.
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No macro split thrives on processed foods alone. Focus on nutrients and whole-food sources:
Protein Sources:
• Lean meats (chicken, turkey)
• Fish rich in omega-3s (salmon, mackerel)
• Plant-based proteins (lentils, chickpeas, tofu)
• Dairy or fortified alternatives (Greek yogurt, cottage cheese)
Carbohydrate Sources:
• Whole grains (oats, brown rice, quinoa)
• Non-starchy vegetables (leafy greens, broccoli, peppers)
• Fruits (berries, apples, pears)
• Legumes (beans, lentils)
Healthy Fat Sources:
• Nuts and seeds (almonds, chia, flax)
• Avocado
• Olive oil or flaxseed oil
• Fatty fish (salmon, sardines)
While macro balancing can be done on your own, certain situations call for extra support:
Consider a free, online symptom check, using the doctor approved Ubie Symptom Checker to explore any new or concerning symptoms. And be sure to speak to a doctor about anything serious or potentially life-threatening.
A good macro split for women over 40 typically centers on 25–30% protein, 25–35% healthy fats, and 35–45% carbohydrates, with adjustments based on goals and activity. Remember:
By tailoring your macros, you can support muscle maintenance, stable energy, and hormone balance—helping you feel strong, vibrant, and in control through every decade.
Speak to a doctor if you experience any severe or persistent symptoms or before making major changes to your diet or exercise routine.
(References)
* Manore MM. Exercise and the Institute of Medicine recommendations for nutrition. Curr Sports Med Rep. 2005 Aug;4(4):193-8. doi: 10.1097/01.csmr.0000306206.72186.00. PMID: 16004827.
* American Dietetic Association, Dietitians of Canada, American College of Sports Medicine, Rodriguez NR, Di Marco NM, Langley S. American College of Sports Medicine position stand. Nutrition and athletic performance. Med Sci Sports Exerc. 2009 Mar;41(3):709-31. doi: 10.1249/MSS.0b013e31890eb86. PMID: 19225360.
* Ley SH, Hamdy O, Mohan V, Hu FB. Prevention and management of type 2 diabetes: dietary components and nutritional strategies. Lancet. 2014 Jun 7;383(9933):1999-2007. doi: 10.1016/S0140-6736(14)60613-9. PMID: 24910231; PMCID: PMC4751088.
* Aragon AA, Schoenfeld BJ, Wildman R, Kleiner S, VanDusseldorp T, Taylor L, Earnest CP, Arciero PJ, Wilborn C, Kalman DS, Stout JR, Willoughby DS, Campbell B, Arent SM, Bannock L, Smith-Ryan AE, Antonio J. International society of sports nutrition position stand: diets and body composition. J Int Soc Sports Nutr. 2017;14:16. doi: 10.1186/s12970-017-0174-y. Epub 2017 Jun 14. PMID: 28630601; PMCID: PMC5470183.
* Willoughby D, Hewlings S, Kalman D. Body Composition Changes in Weight Loss: Strategies and Supplementation for Maintaining Lean Body Mass, a Brief Review. Nutrients. 2018 Dec 3;10(12). doi: 10.3390/nu10121876. Epub 2018 Dec 3. PMID: 30513859; PMCID: PMC6315740.
* Hall KD, Ayuketah A, Brychta R, Cai H, Cassimatis T, Chen KY, Chung ST, Costa E, Courville A, Darcey V, Fletcher LA, Forde CG, Gharib AM, Guo J, Howard R, Joseph PV, McGehee S, Ouwerkerk R, Raisinger K, Rozga I, Stagliano M, Walter M, Walter PJ, Yang S, Zhou M. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake. Cell Metab. 2019 Jul 2;30(1):67-77.e3. doi: 10.1016/j.cmet.2019.05.008. Epub 2019 May 16. PMID: 31105044; PMCID: PMC7946062.
* Wohlgemuth KJ, Arieta LR, Brewer GJ, Hoselton AL, Gould LM, Smith-Ryan AE. Sex differences and considerations for female specific nutritional strategies: a narrative review. J Int Soc Sports Nutr. 2021 Apr 1;18(1):27. doi: 10.1186/s12970-021-00422-8. Epub 2021 Apr 1. PMID: 33794937; PMCID: PMC8015182.
* Li A, Li X, Zhou T, Ma H, Heianza Y, Williamson DA, Smith SR, Bray GA, Sacks FM, Qi L. Sleep Disturbance and Changes in Energy Intake and Body Composition During Weight Loss in the POUNDS Lost Trial. Diabetes. 2022 May 1;71(5):934-944. doi: 10.2337/db21-0699. PMID: 35202470; PMCID: PMC9044134.
* van der Merwe C, Münch M, Kruger R. Chronotype Differences in Body Composition, Dietary Intake and Eating Behavior Outcomes: A Scoping Systematic Review. Adv Nutr. 2022 Dec 22;13(6):2357-2405. doi: 10.1093/advances/nmac093. PMID: 36041181; PMCID: PMC9776742.
* Uluçay Kestane V, Baş M. Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease. Nutrients. 2024 Aug 14;16(16). doi: 10.3390/nu16162699. Epub 2024 Aug 14. PMID: 39203835; PMCID: PMC11357554.
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