What triggers a myasthenia gravis crisis and how is it managed?

Reviewed by Yoshinori Abe, MD

Internal Medicine

A myasthenia gravis crisis is a life-threatening worsening of muscle weakness that can impair breathing. Common triggers include infections, emotional or physical stress, surgery, and certain medications such as some antibiotics or beta-blockers. Management typically involves hospitalization, respiratory support (including ventilation if needed), medication adjustments, and therapies like plasmapheresis or IVIG to rapidly reduce circulating antibodies.

If you or a loved one are experiencing worsening weakness, breathing difficulty, or trouble swallowing, don't wait to find answers. A free, instant, online symptom check can help you understand what may be happening and guide your next steps—whether that's seeking urgent care, contacting your neurologist, or preparing questions for your next appointment. Early recognition saves lives.

Reviewed for medical accuracy: 07/14/2026

Important Next Steps

Discover if myasthenia gravis crisis is urgent Learn what’s causing your muscle weakness Find likely causes of sudden breathing trouble See OTC options for related symptoms Find a doctor for myasthenia gravis Discover medically proven home remedies for symptoms Understand if your symptoms suggest a crisis

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Explanation

A myasthenia gravis crisis is a severe condition where muscles become very weak, especially those that help with breathing. This can happen when someone with myasthenia gravis faces triggers like infections, stress, or certain medications.

Triggers

Infections: Illnesses like colds or the flu can make symptoms worse.
Stress: Emotional or physical stress can also be a trigger.
Medications: Some drugs can interfere with muscle function and should be avoided.

Management

Medication Adjustments: Doctors may change the doses of medications to help control symptoms.
Respiratory Support: If breathing is hard, machines might be used to help.
Plasmapheresis or IVIG: These treatments can help remove harmful antibodies from the blood.

It's important for people with myasthenia gravis to work closely with their healthcare providers to manage their condition and avoid triggers when possible. If you're experiencing muscle weakness or breathing difficulties, consider using a symptom checker to help identify potential concerns before consulting with your doctor.

(References)

Claytor B, Cho SM, & Li Y. (2023). Myasthenic crisis. Muscle & nerve, 37114503.
Bershad EM, Feen ES, & Suarez JI. (2008). Myasthenia gravis crisis. Southern medical journal, 18176295.
Ahmed S, Kirmani JF, Janjua N, Alkawi A, Khatri I, Yahia AM, et al. (2005). An Update on Myasthenic Crisis. Current treatment options in neurology, 15676116.

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