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Published on: 12/11/2025
Most infections with the latest Omicron-derived subvariants look like a bad cold: runny or congested nose, sore throat, headache, mild cough, fatigue, sneezing, and body aches; fever and loss of taste/smell are less common but can still occur. There are several factors to consider—including less common symptoms (like GI upset or chest tightness), who’s at higher risk, when to seek urgent care, and what to do next (testing and isolation); see the complete details and next-step guidance below.
As SARS-CoV-2 continues to evolve, emerging subvariants can cause shifts in how people experience COVID-19. Understanding the new COVID variant symptoms helps you recognize infection early, seek appropriate care, and limit spread. Below is a clear, concise overview—based on recent clinical data and public health guidance—of what to watch for.
Most people infected with the latest Omicron-derived subvariants (e.g., XBB.1.5, XBB.1.16 and others) report symptoms similar to earlier Omicron strains, but with subtle differences in frequency and severity. Key new COVID variant symptoms include:
NOTE: Fever and loss of taste or smell have become less common compared to earlier waves, but they can still occur, especially in unvaccinated or immunocompromised individuals.
While many infections remain mild, these symptoms can occur in some people:
According to Wang et al. (2022), Omicron and its sublineages tend to:
This shift explains why many people today feel “like I’m coming down with a bad cold” rather than “I can’t breathe.”
Most healthy, vaccinated adults experience mild disease. However, watch closely if you or a loved one is:
In these groups, even mild symptoms can escalate, so early recognition and treatment are crucial.
While most people recover at home, seek prompt care or call emergency services if you experience any of these serious warning signs:
If you have any potentially life-threatening symptoms, speak to a doctor or visit the nearest emergency department immediately.
Even with vaccines and boosters, the virus continues to mutate. To reduce your risk:
Remember, while most infections are mild, COVID-19 can still be unpredictable. If you notice any alarming signs or simply feel that “something isn’t right,” don’t hesitate—speak to a doctor. Early intervention can make a big difference in outcomes.
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