What are the possible causes of pain between the scrotum and anus?

Reviewed by Yoshinori Abe, MD

Internal Medicine

Pain between the scrotum and anus, known as perineal pain, is most commonly caused by pudendal nerve irritation (pudendal neuralgia) or myofascial trigger points in the pelvic floor muscles. Other potential causes include prostatitis, infections, or injury to the perineal area.

Because perineal pain can stem from many overlapping conditions—some minor and some requiring prompt treatment—self-diagnosis is difficult and often inaccurate. Taking a free, instant, online symptom check can help you identify likely causes based on your specific symptoms, understand urgency, and decide whether to see a primary care doctor, urologist, or pelvic floor specialist next. It's a quick, private way to get clarity before your next step.

Reviewed for medical accuracy: 07/15/2026

What brings you in today?

Can I treat this myself Do I need to see a doctor Where should I go for care I'm concerned about a symptom Concerned about a possible condition My symptoms are getting worse Seeking a second opinion

Not seeing your question? No worries.

Submit your own Question

Explanation

Pain in the area between the scrotum and anus, known as the perineum, can have several causes. One possible cause is related to the pudendal nerve, which can become irritated or compressed, leading to pain. This nerve is responsible for sensation in the perineal area and issues with it can result in discomfort.

Another potential cause is myofascial pain, which involves sensitive areas in the muscles known as trigger points. These trigger points can cause pain to be felt in the perineum.

Additionally, the inferior cluneal nerves, which are part of the network of nerves in the perineal area, can also contribute to pain if they are affected. Understanding the specific cause of pain in this area often requires careful assessment by a healthcare professional. You can get started by taking a free symptom checker assessment to help identify potential causes of your perineal discomfort.

(References)

Anderson RU, Sawyer T, Wise D, Morey A, & Nathanson BH. (2009). Painful myofascial trigger points and pain sites in men with .... The Journal of urology, 19837420.
Darnis B, Robert R, Labat JJ, Riant T, Gaudin C, Hamel A, & Hamel O. (2008). Perineal pain and inferior cluneal nerves: anatomy and .... Surgical and radiologic anatomy : SRA, 18305887.
Robert R, Labat JJ, Riant T, Louppe JM, & Hamel O. (2009). [The pudendal nerve: clinical and therapeutic .... Neuro-Chirurgie, 19748642.

Thinking about asking ChatGPT?Ask me instead

Tell your friends about us.

We would love to help them too.

For First Time Users

What is Ubie’s Doctor’s Note?

We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.

Was this page helpful?

Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.