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Published on: 1/31/2025

Is Left Shoulder Pain a Cause for Concern? Could It Be Related to a Serious Illness Like Cancer?

Left shoulder pain can be a cause for concern, as it may be related to various underlying conditions, including serious illnesses such as cancer. While not all cases of left shoulder pain indicate a severe problem, it is important to evaluate the symptoms carefully and seek medical attention if necessary.

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Explanation

Common Causes of Left Shoulder Pain

Left shoulder pain can arise from a variety of causes, including:

  • Musculoskeletal Issues: Common causes include rotator cuff injuries, tendonitis, bursitis, or shoulder impingement. These conditions are often related to overuse or injury and can cause localized pain and discomfort.
  • Cervical Spine Problems: Issues in the neck, such as herniated discs or cervical radiculopathy, can lead to referred pain in the shoulder area.
  • Injuries: Trauma to the shoulder, such as fractures or dislocations, can cause significant pain and limit movement.

Serious Causes of Left Shoulder Pain

While many cases of left shoulder pain are benign, there are serious conditions that can present with shoulder pain:

  • Cardiac Issues: Pain in the left shoulder can sometimes be a sign of heart problems, such as angina or a heart attack, especially if accompanied by other symptoms like chest pain, shortness of breath, or nausea.
  • Pancoast Tumor: This type of lung cancer can cause shoulder pain due to its location at the top of the lung, affecting nearby structures. Smokers or individuals with a history of lung cancer should be particularly aware of this possibility.
  • Lung Cancer: Other forms of lung cancer can also present as shoulder pain, especially if the tumor is pressing on nerves or other structures in the chest.
  • Referred Pain from Abdominal Issues: Conditions such as splenic or pancreatic problems can also cause referred pain to the left shoulder.

When to Seek Medical Attention

If you experience persistent or severe left shoulder pain, especially if it is accompanied by other concerning symptoms (such as unexplained weight loss, fatigue, fever, or changes in appetite), it is important to seek medical attention. A healthcare provider can perform a thorough evaluation, including a physical examination and imaging studies, to determine the underlying cause of the pain.

(References)

  • Khoo S. An 80-year-old woman with left shoulder pain. Malays Fam Physician. 2010 Dec 31;5(3):139-44. PMID: 25606206; PMCID: PMC4170415.

  • Al Shammari M, Hassan A, Al Jawad M, Farea A, Almansour A, Al Yousif G, Sebiany A, Bin Bakr Z. Pancoast Tumor: The Overlooked Etiology of Shoulder Pain in Smokers. Am J Case Rep. 2020 Sep 11;21:e926643. doi: 10.12659/AJCR.926643. PMID: 32913177; PMCID: PMC7508304.

  • Weber B, Luke ND, Payette AM, Shaaban H. Lung Cancer Presenting as Upper Extremity Musculoskeletal Pain: A Case Report. Cureus. 2022 Sep 2;14(9):e28706. doi: 10.7759/cureus.28706. PMID: 36204042; PMCID: PMC9527109.

  • Slaven EJ, Mathers J. Differential diagnosis of shoulder and cervical pain: a case report. J Man Manip Ther. 2010 Dec;18(4):191-6. doi: 10.1179/106698110X12804993426884. PMID: 22131792; PMCID: PMC3113270.

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