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Published on: 9/10/2026

What are the chances of complications when pregnant at 38?

At 38, most pregnancies end in a healthy birth, though risks rise modestly with age: miscarriage occurs in roughly 20 to 25 percent of pregnancies, the chance of a chromosomal condition such as Down syndrome is about 1 in 175, and rates of gestational diabetes, preeclampsia, placental problems, preterm delivery, and cesarean birth are all somewhat higher than in your twenties. Your personal odds depend on far more than your age, including blood pressure, weight, whether you smoke, prior pregnancy history, and whether you are carrying multiples. Screening tests, early prenatal care, and closer monitoring meaningfully reduce many of these risks. There are several important factors and warning signs to consider, so see below to understand more.

If you are pregnant or planning to be at 38 and noticing symptoms like cramping, spotting, swelling, severe headaches, or unusual fatigue, a free, instant, online symptom check can help you see which possible causes fit your situation and how urgently you should contact your provider, so you walk into that appointment informed rather than anxious.

Last reviewed for medical accuracy: 09/10/2026

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Explanation

Pregnant at 38: Chances of Complications

Being pregnant at 38 is increasingly common. Advances in fertility treatments, shifting life priorities and better prenatal care mean many women choose to start or expand their families later. If you’re pregnant at 38, chances of complications are higher than in younger mothers—but most pregnancies still end in healthy births. This guide breaks down the most common risks, how to reduce them, and when to get extra support.

Understanding Advanced Maternal Age

Medical experts define “advanced maternal age” (AMA) as 35 or older at the time of delivery. At AMA, your body and your baby’s development require a little extra monitoring. Key points:

  • Egg quality and quantity begin to decline more noticeably after age 35.
  • Chromosomal changes in eggs can increase the chance of genetic conditions.
  • Pre-existing health issues—like high blood pressure or diabetes—are more common by age 38.

Common Risks and Statistics

While most 38-year-olds have healthy pregnancies, here are some data points from reputable sources (ACOG, CDC):

  1. Miscarriage and Chromosomal Abnormalities

    • Miscarriage risk at age 38: around 20–25%, compared to 10–15% in women under 35.
    • Down syndrome risk at age 38: about 1 in 150, rising from 1 in 350 at age 35.
  2. Gestational Diabetes

    • Incidence in women over 35: about 8–10%, versus 5–6% in younger mothers.
    • Early screening between weeks 24–28 helps catch and manage high blood sugar.
  3. High Blood Pressure and Preeclampsia

    • Chronic hypertension before pregnancy: more likely after age 35.
    • Preeclampsia (pregnancy-induced high blood pressure with organ involvement) affects 3–5% of all pregnancies, slightly higher in AMA.
  4. Preterm Birth and Low Birth Weight

    • Preterm birth (before 37 weeks): 12–14% in AMA vs. 10% overall.
    • Low birth weight (under 5 lbs 8 oz): risk increases modestly with age.
  5. Cesarean Delivery

    • C-section rates climb from about 26% in women under 35 to 30–35% in those over 35, often tied to baby position or maternal health issues.

Screening and Diagnostic Options

Pregnant at 38? Early and targeted testing gives you information and choices:

  • Non-Invasive Prenatal Testing (NIPT)
    • Blood test as early as 10 weeks to screen for chromosome conditions.
    • Accuracy over 99% for common trisomies (21, 18, 13).
  • First-Trimester Combined Screening
    • Ultrasound measurement of nuchal translucency plus blood markers.
  • Diagnostic Tests (Invasive)
    • Chorionic Villus Sampling (CVS) around 10–12 weeks.
    • Amniocentesis around 15–20 weeks.
    • Both carry a small risk of miscarriage (about 0.1–0.3%).

Reducing Your Risks

You can’t control age, but you can boost your odds of a smooth pregnancy. Simple steps:

  • Start prenatal vitamins with at least 400 mcg folic acid before conception.
  • Aim for a healthy weight: follow your doctor’s guidelines on BMI.
  • Eat a balanced diet rich in whole grains, lean proteins, fruits and vegetables.
  • Exercise regularly (150 minutes of moderate activity weekly), unless advised otherwise.
  • Manage chronic conditions (hypertension, diabetes) before and during pregnancy.
  • Keep up with dental check-ups—gum disease can affect pregnancy outcomes.
  • Avoid alcohol, tobacco and recreational drugs.

When to Seek Extra Support

Even with all precautions, new symptoms can pop up. If you notice anything concerning—severe headaches, visual changes, sudden swelling, bleeding or severe pain—don’t wait. You can also try a free, online symptom check, using the doctor approved Ubie Symptom Checker to get guidance on next steps and decide if you need urgent care.

The Importance of Regular Prenatal Care

Frequent check-ups are your best defense against complications:

  • First visit by 8–10 weeks to review health history, labs and early ultrasound.
  • Visits every 4 weeks until 28 weeks, every 2–3 weeks until 36 weeks, then weekly.
  • Monitor blood pressure, weight gain, baby’s growth and heartbeat.
  • Screen for gestational diabetes, anemia and infections at recommended times.

Preparing for Labor and Delivery

Discuss your birth plan and possible scenarios with your provider:

  • Vaginal birth expectations and indications for induction.
  • C-section risks and recovery.
  • Pain-management options, including epidurals or nitrous oxide.
  • Early breastfeeding support—older mothers benefit from lactation counseling.

Remember to Speak to a Doctor

Information is power, but it’s no substitute for personalized medical care. If you experience serious symptoms—heavy bleeding, chest pain, shortness of breath, decreased fetal movement—call your provider or go to the nearest emergency department immediately. Always speak to a doctor about anything that could be life threatening or serious.


By understanding the data on pregnant at 38 chances of complications, staying proactive with screenings and maintaining open communication with your healthcare team, you’ll give yourself and your baby the best possible start. Wishing you a healthy, joyful journey to parenthood!

(References)

  • * Lean SC, Derricott H, Jones RL, Heazell AEP. Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis. PLoS One. 2017;12(10):e0186287. doi: 10.1371/journal.pone.0186287. Epub 2017 Oct 17. PMID: 29040334; PMCID: PMC5645107.

  • * Frederiksen LE, Ernst A, Brix N, Braskhøj Lauridsen LL, Roos L, Ramlau-Hansen CH, Ekelund CK. Risk of Adverse Pregnancy Outcomes at Advanced Maternal Age. Obstet Gynecol. 2018 Mar;131(3):457-463. doi: 10.1097/AOG.0000000000002504. PMID: 29420406.

  • * Magnus MC, Wilcox AJ, Morken NH, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ. 2019 Mar 20;364:l869. doi: 10.1136/bmj.l869. Epub 2019 Mar 20. PMID: 30894356; PMCID: PMC6425455.

  • * Pinheiro RL, Areia AL, Mota Pinto A, Donato H. Advanced Maternal Age: Adverse Outcomes of Pregnancy, A Meta-Analysis. Acta Med Port. 2019 Mar 29;32(3):219-226. doi: 10.20344/amp.11057. Epub 2019 Mar 29. PMID: 30946794.

  • * Frick AP. Advanced maternal age and adverse pregnancy outcomes. Best Pract Res Clin Obstet Gynaecol. 2021 Jan;70:92-100. doi: 10.1016/j.bpobgyn.2020.07.005. Epub 2020 Jul 15. PMID: 32741623.

  • * Correa-de-Araujo R, Yoon SSS. Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age. J Womens Health (Larchmt). 2021 Feb;30(2):160-167. doi: 10.1089/jwh.2020.8860. Epub 2020 Nov 13. PMID: 33185505; PMCID: PMC8020515.

  • * Guarga Montori M, Álvarez Martínez A, Luna Álvarez C, Abadía Cuchí N, Mateo Alcalá P, Ruiz-Martínez S. Advanced maternal age and adverse pregnancy outcomes: A cohort study. Taiwan J Obstet Gynecol. 2021 Jan;60(1):119-124. doi: 10.1016/j.tjog.2020.11.018. PMID: 33494983.

  • * Saccone G, Gragnano E, Ilardi B, Marrone V, Strina I, Venturella R, Berghella V, Zullo F. Maternal and perinatal complications according to maternal age: A systematic review and meta-analysis. Int J Gynaecol Obstet. 2022 Oct;159(1):43-55. doi: 10.1002/ijgo.14100. Epub 2022 Feb 7. PMID: 35044694; PMCID: PMC9543904.

  • * Sparić R, Stojković M, Plešinac J, Pecorella G, Malvasi A, Tinelli A. Advanced maternal age (AMA) and pregnancy: a feasible but problematic event. Arch Gynecol Obstet. 2024 Sep;310(3):1365-1376. doi: 10.1007/s00404-024-07678-w. Epub 2024 Aug 9. PMID: 39120753.

  • * Pécheux O, Pesenti L, Martinez De Tejada B, Le Tinier B. [Pregnancies at advanced maternal age]. Rev Med Suisse. 2024 Oct 16;20(891):1874-1879. doi: 10.53738/REVMED.2024.20.891.1874. PMID: 39429175.

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