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Published on: 9/17/2026
Lowering a high RDW (red cell distribution width) depends on treating the underlying cause, most often nutrient deficiencies such as low iron, vitamin B12, or folate, which are typically addressed with dietary changes, supplements, or treatment of blood loss. Other drivers include chronic inflammation, liver or kidney disease, thyroid problems, recent blood transfusion, and certain medications, so the right fix varies by person and there is no single way to bring the number down quickly. Because RDW is interpreted alongside hemoglobin, MCV, and other markers, a mildly elevated result can be harmless in some cases and meaningful in others, and there are several important factors and timelines to consider before assuming a cause; see below to understand more.
If your RDW is flagged as high and you are unsure whether it points to a simple deficiency or something that needs prompt attention, a free, instant, online symptom check can help you connect your lab result to any symptoms you have been noticing. It takes only a few minutes, is available anytime, and gives you a clearer sense of possible causes and which follow-up tests or specialists to discuss with your doctor next.
Last reviewed for medical accuracy: 09/17/2026
How to Lower a High RDW on Your Blood Test
If your latest blood work shows a high RDW (Red Cell Distribution Width), you may be wondering what it means and how to bring it into a healthier range. RDW measures the variation in size of your red blood cells. A high RDW on your blood test often signals underlying issues like nutrient deficiencies or chronic conditions. This guide will walk you through practical steps, based on credible medical sources, to help you address a high RDW.
What Does a High RDW Mean?
Red cell distribution width (RDW) is reported as part of a standard complete blood count (CBC). It reflects how evenly sized your red blood cells (RBCs) are. When RDW is elevated, it means there’s a wide variation in cell size—some small, some large. Common causes include:
A small rise in RDW isn’t necessarily alarming, but it does warrant further evaluation to find and treat any underlying problems.
Key Strategies to Lower a High RDW
Correct Nutrient Deficiencies
Nutrient shortages are among the most common drivers of high RDW.
Iron
• Why it matters: Iron is essential for making healthy red blood cells.
• What to do:
Vitamin B12 and Folate
• Why they matter: Both are needed for DNA synthesis in red blood cells.
• What to do:
Manage Chronic Conditions
Inflammation and chronic diseases can disrupt red blood cell production, widening cell size variation.
Optimize Your Diet and Lifestyle
Overall health impacts your blood cell production and size uniformity.
• Balanced Diet:
Review Medications
Certain drugs can affect red blood cell production or lifespan, contributing to a high RDW.
Follow Up with Repeat Testing
After making dietary and lifestyle changes—or treating an underlying condition—your RDW should trend back toward normal.
• Timing: Work with your doctor to schedule a repeat CBC in 8–12 weeks.
• Tracking: Note any new symptoms or changes in energy, bruising, or bleeding.
• Adjustments: If RDW remains high, further investigation (e.g., iron studies, B12/folate levels, bone marrow biopsy) may be needed.
When to Seek Medical Advice
Most causes of high RDW are treatable, but prompt evaluation is key. You should speak to a doctor if you experience:
For a quick check of your symptoms and to help determine urgency, consider a free, online symptom check, using the doctor approved Ubie Symptom Checker.
Tips for Talking with Your Doctor
Key Takeaways
Remember, while you can take many positive steps on your own, never ignore symptoms that could signal a serious problem. Always speak to a doctor about anything life-threatening or persistent—your health deserves individualized attention.
(References)
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* Ludwik TM, Heinrich DA, Rendahl A, Friedenberg SG. Red cell distribution width is a predictor of all-cause mortality in hospitalized dogs. J Vet Emerg Crit Care (San Antonio). 2022 Jan;32(1):9-17. doi: 10.1111/vec.13109. Epub 2021 Aug 25. PMID: 34432939; PMCID: PMC9272852.
* Akcal MA, Eke I. Post-Operative Red Cell Distribution Width Increase May Predict Mortality in Patients Operated for Hip Fracture. Clin Lab. 2021 Nov 1;67(11). doi: 10.7754/Clin.Lab.2021.210337. PMID: 34758234.
* Kelly PD, Dambrino RJ, Guidry BS, Tang AR, Stewart TG, Mistry A, Morone PJ, Chambless LB. Red blood cell distribution width in glioblastoma. Clin Neurol Neurosurg. 2022 Feb;213:107096. doi: 10.1016/j.clineuro.2021.107096. Epub 2021 Dec 24. PMID: 34973653.
* Marom O, Paz I, Topaz G, Ohana N, Yaacobi E. Red cell distribution width-A mortality predictor in older adults with proximal femoral fracture. Arch Gerontol Geriatr. 2022 May-Jun;100:104623. doi: 10.1016/j.archger.2022.104623. Epub 2022 Jan 19. PMID: 35078053.
* Kim KM, Nerlekar R, Tranah GJ, Browner WS, Cummings SR. Higher red cell distribution width and poorer hospitalization-related outcomes in elderly patients. J Am Geriatr Soc. 2022 Aug;70(8):2354-2362. doi: 10.1111/jgs.17819. Epub 2022 May 4. PMID: 35506925.
* Du D, Zhang L, Wen X, Zhang XM, Yuan YD. Machine learning model and hemoglobin to red cell distribution width ratio evaluates all-cause mortality in pulmonary embolism. Sci Rep. 2025 Jul 2;15(1):23070. doi: 10.1038/s41598-025-07431-6. Epub 2025 Jul 2. PMID: 40594595; PMCID: PMC12216644.
* Liu F, Lin B, Huang W, Dai J, Hu Y, Wu Z, Xu G, Xie L, Wang T. Association Between Hemoglobin-to-Red Blood Cell Distribution Width Ratio and Arterial Stiffness. J Clin Hypertens (Greenwich). 2025 Sep;27(9):e70141. doi: 10.1111/jch.70141. PMID: 40947749; PMCID: PMC12434183.
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