Published on: 5/21/2025
The sciatic nerve is the largest nerve in the body, starting in the lower back and running down the back of each leg.
The sciatic nerve is a major nerve that runs from the lower back down through the hips and buttocks and along each leg. It is the largest nerve in the human body.
Understanding the path and function of the sciatic nerve helps in diagnosing and treating conditions like sciatica, where pain radiates along the nerve’s pathway.
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