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Published on: 9/28/2026

Spleen Pain: Where You Feel It and What Causes Pain There

Spleen pain is typically felt in the upper left abdomen just under the ribs, and it can radiate to the left shoulder or back, sometimes worsening with deep breaths. Common causes include an enlarged spleen from infections like mononucleosis, liver disease, blood disorders such as sickle cell anemia, certain cancers, and trauma that bruises or ruptures the organ. Because spleen pain can mimic stomach, heart, or lung problems, and because a ruptured spleen is a medical emergency, the specific location, timing, and accompanying symptoms matter greatly. Several important distinctions and warning signs are outlined below, so review the complete answer before deciding what to do next.

Since upper left abdominal pain has many overlapping explanations, a free, instant, online symptom check can help you sort likely causes from urgent ones and clarify whether you should monitor at home, book a visit, or seek care immediately.

Last reviewed for medical accuracy: 09/28/2026

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Explanation

Spleen Pain: Where You Feel It and What Causes Pain There

Spleen pain can be unsettling, especially when you’re not sure what’s behind the discomfort. Understanding where spleen pain occurs, what might trigger it, and when to seek help can give you clarity—and help you take appropriate action. Below is a detailed guide based on credible medical sources to help you recognize, understand, and address spleen pain.

Anatomy and Location of the Spleen

  • The spleen sits in the upper left side of the abdomen, just under the rib cage.
  • It lies behind the stomach and in front of the left kidney.
  • In most adults, it measures about 4–5 inches long (roughly the size of a fist).
  • Because of its protected position under the ribs, direct injury is less common—but the spleen can still become painful or enlarged.

Where You Feel Spleen Pain

People describe spleen pain in different ways, but common features include:

  • Left upper quadrant ache: A dull or sharp pain under the left ribs.
  • Left shoulder or back pain: Irritation of the diaphragm can refer pain to the shoulder (Kehr’s sign).
  • Abdominal fullness or tightness: Often linked to spleen enlargement pushing against adjacent organs.
  • Pain when breathing deeply: Pressure on the diaphragm may worsen discomfort with each breath.

Pay attention to any combination of these sensations, especially if they persist or worsen over hours or days.

Common Causes of Spleen Pain

  1. Splenic Enlargement (Splenomegaly)
    • Viral infections (e.g., mononucleosis)
    • Bacterial infections (e.g., endocarditis, tuberculosis)
    • Blood disorders (e.g., hemolytic anemia, lymphoma)
    • Liver diseases (e.g., cirrhosis with portal hypertension)
  2. Infections and Inflammation
    • Mononucleosis (Epstein–Barr virus): Often causes marked spleen enlargement and pain.
    • Bacterial infections: Can lead to abscess formation or generalized inflammation.
    • Parasitic infections (e.g., malaria): May inflame the spleen.
  3. Trauma or Injury
    • Blunt trauma to the left side (e.g., car accidents, sports injuries) can cause splenic laceration or rupture.
    • Sudden, severe pain may suggest internal bleeding—this is an emergency.
  4. Infarction (Restricted Blood Flow)
    • Blood clots or emboli in splenic vessels can starve tissue of oxygen, leading to sharp, localized pain.
    • Often associated with conditions like sickle cell disease or clotting disorders.
  5. Cysts and Tumors
    • Benign cysts may grow large enough to cause discomfort.
    • Malignant tumors (primary or metastatic) can cause pain by stretching the splenic capsule.
  6. Hematological Disorders
    • Conditions like leukemia and lymphoma can enlarge the spleen and lead to pain or a sense of fullness.
  7. Other Causes
    • Splenic artery aneurysm
    • Autoimmune disorders (e.g., lupus)
    • Rare congenital abnormalities

Signs That Warrant Immediate Attention

Certain symptoms accompanying spleen pain may indicate a serious or life-threatening condition. Seek emergency care or call emergency services if you experience:

  • Sudden, severe left upper abdominal or shoulder pain
  • Lightheadedness, fainting, or signs of shock (cold sweat, rapid heartbeat)
  • Unexplained rapid heart rate or low blood pressure
  • Difficulty breathing
  • Abdominal rigidity or guarding (involuntary tensing of abdominal muscles)

If you suspect an injury to your spleen or internal bleeding, do not delay—prompt medical evaluation is essential.

Diagnosis: How Doctors Determine the Cause

When you see a healthcare professional for spleen pain, they may use:

  • Medical History and Physical Exam
    • Palpation of the left upper quadrant to assess spleen size and tenderness
    • Evaluation for signs of anemia, infection, or bleeding
  • Blood Tests
    • Complete blood count (CBC) to check for anemia, infection, or blood disorders
    • Liver function tests and markers of inflammation
  • Imaging Studies
    • Ultrasound: First-line, noninvasive way to assess spleen size and structure
    • CT scan: Detailed imaging to detect lacerations, infarctions, or masses
    • MRI: Useful for soft-tissue evaluation
  • Other Tests
    • Viral serologies (e.g., Epstein–Barr virus)
    • Blood cultures if infection is suspected
    • Biopsy (rarely) when lymphoma or other malignancy is a concern

Treatment Options

Treatment for spleen pain depends on the underlying cause:

  • Observation and Rest
    • Mild splenomegaly from a viral infection often resolves with rest, hydration, and over-the-counter pain relievers.
  • Medication
    • Antibiotics for bacterial infections
    • Antiparasitics for malaria or other parasitic causes
    • Blood thinners or clot-dissolving agents for splenic infarction
  • Surgical Intervention
    • Splenectomy (removal of the spleen) may be necessary for severe trauma, uncontrollable bleeding, or certain hematologic conditions.
    • Partial splenectomy or spleen-saving procedures in select cases.
  • Supportive Care
    • Blood transfusions if anemia is severe
    • Pain management and electrolyte balance

Post-treatment, you may need vaccinations (e.g., pneumococcal, meningococcal) if your spleen has been removed, as the spleen plays a key role in fighting certain infections.

Self-Care and Home Management

While under a doctor’s guidance, you can often support your recovery with:

  • Gentle rest and gradual return to activity
  • Acetaminophen or ibuprofen for mild pain (follow dosing instructions)
  • Adequate hydration and balanced nutrition
  • Avoiding contact sports or heavy lifting if your spleen is enlarged
  • Monitoring for increasing pain, fever, or new symptoms

When to Use an Online Symptom Checker

If you notice early or mild symptoms and want guidance before seeing a doctor, consider a free, online symptom check, using the doctor approved Ubie Symptom Checker. This tool can help you:

  • Clarify which symptoms are most concerning
  • Identify possible causes based on your inputs
  • Decide whether you need urgent care or a routine doctor’s appointment

Preventing Spleen-Related Complications

While some causes of spleen pain aren’t avoidable, you can reduce risks by:

  • Using protective gear in contact sports and high-risk activities
  • Managing chronic conditions (e.g., sickle cell disease, liver disease) under medical supervision
  • Keeping up to date with vaccinations recommended after splenectomy
  • Seeking prompt care for infections that could spread to the spleen

Key Takeaways

  • Spleen pain typically presents as discomfort under the left ribs, sometimes felt in the left shoulder or back.
  • Common causes include infections, trauma, splenic enlargement, infarction, and hematological disorders.
  • Sudden severe pain, signs of internal bleeding, or systemic symptoms require immediate medical attention.
  • Diagnosis often involves physical exams, blood tests, and imaging studies.
  • Treatment ranges from rest and medication to surgical intervention for severe cases.
  • Use the Ubie Symptom Checker for a free, online symptom check that’s doctor approved—and follow up with a healthcare provider as needed.

Remember, this information is meant to help you understand spleen pain—not replace professional medical advice. Always speak to a doctor if you experience severe, persistent, or worsening pain, or any symptoms that could be life threatening or serious.

(References)

  • * Herrera Merino N, Díaz del Río Botas M, Marinelli Ibarreta A, San José Borreguero A, Abascal Morte J, Colas Vicente A. [Acute abdomen caused by spontaneous rupture of splenic hydatid cyst]. Rev Esp Enferm Dig. 1990 Aug;78(2):102-4. PMID: 2271290.

  • * Bernat S, García Boyero R, Guinot M, López F, Gozalbo T, Cañigral G. Pathologic rupture of the spleen as the initial manifestation in acute lymphoblastic leukemia. Haematologica. 1998 Aug;83(8):760-1. PMID: 9793269.

  • * Wong M, See JY, Sufyan W, Diddapur RK. Splenic infarction. A rare presentation of anaplastic pancreatic carcinoma and a review of the literature. JOP. 2008 Jul 10;9(4):493-8. Epub 2008 Jul 10. PMID: 18648141.

  • * Privitera A, Milkhu C, Datta V, Sayegh M, Cohen R, Windsor A. Spontaneous rupture of the spleen in type IV Ehlers-Danlos syndrome: report of a case. Surg Today. 2009;39(1):52-4. doi: 10.1007/s00595-007-3782-3. Epub 2009 Jan 8. PMID: 19132469.

  • * El-Khoury EF, Souaiby MC, Aftimos GP. Epidermoid cyst of the spleen: case report. J Med Liban. 2009 Oct-Dec;57(4):268-70. PMID: 20027806.

  • * Ihedioha U, Syed A, Lloyd G, Scott A. Conservative treatment of splenic infarction and intestinal obstruction caused by a wandering spleen. Scott Med J. 2014 May;59(2):e18-20. doi: 10.1177/0036933014530847. Epub 2014 Apr 3. PMID: 24700108.

  • * Batagini NC, Gornik H, Kirksey L. Spontaneous Splenic Rupture in Vascular Ehlers-Danlos Syndrome. Vasc Endovascular Surg. 2015 Jul-Aug;49(5-6):152-4. doi: 10.1177/1538574415602783. Epub 2015 Aug 30. PMID: 26323967.

  • * Bhattarai P, Pierr L, Adeyinka A, Sadanandan S. Splenic Infarct: A Rare Presentation in a Pediatric Patient. JNMA J Nepal Med Assoc. 2014 Oct-Dec;52(196):1017-9. PMID: 26982903.

  • * Demirel A, Hansen MA, Sunesen KG, Nerstrøm P. [Wandering spleen in a patient hospitalized with acute abdomen]. Ugeskr Laeger. 2017 Jun 19;179(25). PMID: 28648152.

  • * Agarwal N, Sharma A, Garg G. Non-traumatic ruptured splenic abscess presenting with pneumoperitoneum in an immunocompetent patient: a diagnostic dilemma. BMJ Case Rep. 2019 May 8;12(5). doi: 10.1136/bcr-2018-228961. Epub 2019 May 8. PMID: 31068349; PMCID: PMC6506054.

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