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Published on: 10/30/2025

Does the prognosis change if stage 4 prostate cancer is responsive to hormone therapy?

If stage 4 prostate cancer responds well to hormone therapy, the prognosis can improve, as early PSA response is a good sign. See below to understand more.

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Explanation

When stage 4 prostate cancer responds to hormone therapy, it can lead to a better prognosis. The medical literature highlights that an early drop in prostate-specific antigen (PSA) levels is a key indicator of a positive response to treatment.

  1. Early Response: Studies show that if PSA levels decrease within the first six months of hormone therapy, it suggests that the cancer is responding well. This early response is linked to better outcomes.

  2. Prognostic Factor: A significant PSA response is considered a good sign and can be used as a prognostic factor. This means that if the PSA levels drop quickly, there is a higher chance of a better prognosis.

  3. Monitoring: Regular monitoring of PSA levels is crucial during treatment. It helps doctors understand how well the cancer is responding and adjust the treatment plan if necessary.

Overall, a good response to hormone therapy, especially seen through early PSA level reductions, can improve the outlook for patients with stage 4 prostate cancer.

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