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Published on: 10/22/2026

Which Supplements Are Stopped Before Surgery for Bleeding Risk

Several supplements are commonly stopped 1 to 2 weeks before surgery because they can thin the blood or interfere with clotting, including fish oil, vitamin E, garlic, ginger, ginkgo biloba, ginseng, turmeric or curcumin, dong quai, feverfew, saw palmetto, and high-dose vitamin C, though timing varies by product, dose, and procedure. There are several important factors to consider, including your other medications, anesthesia plans, and surgeon-specific instructions, so see below to understand more before you stop or continue anything.

If you are noticing easy bruising, unusual bleeding, or symptoms that make you unsure whether your supplements are affecting you, getting clarity early matters because pre-surgical bleeding risk is easier to manage before the day of your procedure. A free, instant, online symptom check can help you organize what you are experiencing, flag issues worth raising with your surgeon or anesthesiologist, and point you toward the right next step. It takes just a few minutes, costs nothing, and gives you a clearer starting point for the conversation that protects your surgery.

Last reviewed for medical accuracy: 10/22/2026

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Explanation

Supplements to Stop Before Surgery for Bleeding Risk

Preparing for surgery involves more than fasting and paperwork. Certain dietary supplements can increase bleeding risk and interfere with anesthesia or wound healing. To lower your risk, your healthcare team will likely ask you to pause specific supplements before your procedure. Below is a clear guide on supplements to stop before surgery bleeding, based on credible medical sources.


Why Stop Supplements Before Surgery?

  • Many herbal and dietary supplements affect blood clotting, blood pressure, or anesthesia safety.
  • Uncontrolled bleeding during or after surgery can lead to complications such as:
    • Prolonged operation time
    • Need for blood transfusions
    • Delayed wound healing
  • Anesthesia providers need full control of your blood pressure and clotting function.

In general, most supplements with blood-thinning properties should be stopped 7–14 days before surgery. However, always follow the timeline your surgeon or anesthesiologist provides.


Common Supplements That Increase Bleeding Risk

Below are the most frequently used supplements associated with increased bleeding. If you take any of these, mention them to your care team as early as possible.

1. Fish Oil (Omega-3 Fatty Acids)

  • Why it matters: May reduce platelet aggregation.
  • Stop: 7–10 days before surgery.

2. Vitamin E

  • Why it matters: At high doses, it can interfere with vitamin K–dependent clotting factors.
  • Stop: 7–14 days before surgery.

3. Garlic Supplements

  • Why it matters: Allicin and other compounds may inhibit platelet function.
  • Stop: 7 days before surgery.

4. Gingko Biloba

  • Why it matters: Can inhibit platelet-activating factor.
  • Stop: 7 days before surgery.

5. Ginseng (Asian and American)

  • Why it matters: May reduce clotting and affect blood sugar.
  • Stop: 7 days before surgery.

6. St. John’s Wort

  • Why it matters: Affects drug-metabolizing enzymes; can alter anesthesia drug levels.
  • Stop: 14 days before surgery.

7. Turmeric (Curcumin)

  • Why it matters: Inhibits platelets and can interact with blood thinners.
  • Stop: 7 days before surgery.

8. Ginger

  • Why it matters: May have mild anti-platelet effects, especially if taken in large amounts.
  • Stop: 7 days before surgery.

9. Evening Primrose Oil

  • Why it matters: Contains gamma-linolenic acid, which may increase bleeding.
  • Stop: 7 days before surgery.

10. Willow Bark

  • Why it matters: Contains salicylates (similar to aspirin) that can thin the blood.
  • Stop: 7 days before surgery.

11. Dong Quai

  • Why it matters: Traditional herbal remedy that can act as a blood thinner.
  • Stop: 7 days before surgery.

12. Feverfew

  • Why it matters: May inhibit platelet aggregation.
  • Stop: 7 days before surgery.

13. Bromelain (Pineapple Enzyme)

  • Why it matters: Can reduce clotting and increase bleeding risk.
  • Stop: 7 days before surgery.

Other Herbs and Supplements to Consider

Even if a supplement isn’t on the above list, always disclose every vitamin, mineral, herb, or “natural” product you use. Other supplements sometimes linked to bleeding or anesthesia interactions include:

  • Black Cohosh
  • Kava
  • Goldenseal
  • Licorice Root
  • Valerian (may interact with sedatives)
  • Mistletoe

How Long Should You Stop Supplements?

  • Standard recommendation: 7–14 days before surgery for most supplements.
  • Exceptions:
    • Fish oil: Some providers suggest 10 days.
    • St. John’s Wort: Up to 14 days (due to enzyme effects).
  • Why timing matters: Supplements circulate in your body for days to weeks; stopping early reduces residual effects.

Always confirm timing with your surgeon or anesthesiologist, as individual factors (dose, frequency, other medications) can alter recommendations.


Tips for a Smooth Pre-Op Process

  1. Make a complete list
    Include all prescription drugs, over-the-counter medications, vitamins, minerals, herbs, and “health powders.”
  2. Share your list
    Give copies to your surgeon, anesthesiologist, dentist (if having dental surgery), and primary care provider.
  3. Ask questions
    If you’re unsure why you’ve been told to stop something, ask for a clear explanation.
  4. Keep communications open
    Let your care team know about any changes—new supplements or health issues—right away.
  5. Be cautious with “natural” claims
    Just because something is labeled natural doesn’t mean it’s safe around surgery.

Managing Anxiety and Staying Prepared

It’s normal to feel some anxiety before surgery. Knowledge is power:

  • Use a free, online symptom check, using the doctor approved Ubie Symptom Checker to explore any symptoms or concerns you have leading up to surgery.
  • Practice relaxation techniques such as deep breathing, guided imagery, or gentle stretching (if approved by your medical team).
  • Follow any pre-operative instructions on diet, medication, and smoking/alcohol cessation carefully.

Speak to a Doctor

This guide provides an overview of supplements to stop before surgery bleeding but cannot replace personalized medical advice. Speak to your surgeon, anesthesiologist, or primary care provider about any supplement, symptom, or concern—especially if you experience:

  • Unusual bruising or bleeding
  • Persistent headaches, dizziness, or fainting
  • Signs of infection (fever, swelling, redness at a wound site)
  • Any side effect you find concerning

Your healthcare team wants you to have the safest surgery and smoothest recovery possible. Always prioritize their recommendations and report changes promptly.


By pausing these supplements and following your provider’s instructions, you reduce bleeding risk and help ensure the best surgical outcome. Good luck with your procedure, and remember: open communication with your care team is key to a safe, successful surgery.

(References)

  • * Smedley F, Bowling T, James M, Stokes E, Goodger C, O'Connor O, Oldale C, Jones P, Silk D. Randomized clinical trial of the effects of preoperative and postoperative oral nutritional supplements on clinical course and cost of care. Br J Surg. 2004 Aug;91(8):983-90. doi: 10.1002/bjs.4578. PMID: 15286958.

  • * Meara JG, Smith EM, Harshbarger RJ, Farlo JN, Matar MM, Levy ML. Blood-conservation techniques in craniofacial surgery. Ann Plast Surg. 2005 May;54(5):525-9. doi: 10.1097/01.sap.0000157901.57961.3b. PMID: 15838215.

  • * Thapa BR. Therapeutic potentials of bovine colostrums. Indian J Pediatr. 2005 Oct;72(10):849-52. doi: 10.1007/BF02731112. PMID: 16272656.

  • * Patel N. Herbal interactions. Br Dent J. 2010 Jul 24;209(2):57. doi: 10.1038/sj.bdj.2010.632. PMID: 20651752.

  • * Parolia A. Herbal history. Br Dent J. 2010 Oct 23;209(8):368. doi: 10.1038/sj.bdj.2010.932. PMID: 20966981.

  • * Elia M. Oral nutritional support in patients with cancer of the gastrointestinal tract. J Hum Nutr Diet. 2011 Oct;24(5):417-20. doi: 10.1111/j.1365-277X.2011.01204.x. PMID: 21884286.

  • * Scott MJ, Fawcett WJ. Oral carbohydrate preload drink for major surgery - the first steps from famine to feast. Anaesthesia. 2014 Dec;69(12):1308-13. doi: 10.1111/anae.12921. Epub 2014 Oct 23. PMID: 25346490.

  • * Scott SH, Mota ALS, Loffelmann C, Fettke G, Crofts C. Doubt about pre-operative carbohydrate supplementation. Anaesthesia. 2019 Apr;74(4):540-541. doi: 10.1111/anae.14618. PMID: 30847908.

  • * Weimann A, Wobith M. ESPEN Guidelines on Clinical nutrition in surgery - Special issues to be revisited. Eur J Surg Oncol. 2024 May;50(5):106742. doi: 10.1016/j.ejso.2022.10.002. Epub 2022 Oct 13. PMID: 36280431.

  • * Dekker TJ. Editorial Commentary: Testosterone, Growth Hormone, and Vitamin D Supplementation Is Not Routinely Indicated for Orthopaedic Surgery Patients. Arthroscopy. 2025 Aug;41(8):3151-3152. doi: 10.1016/j.arthro.2025.01.033. Epub 2025 Feb 3. PMID: 39909207.

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