Why Do I Get Swollen Lips After Kissing?

When you kiss, your lips come into contact with many things, like your partner’s saliva, flavors from food, or even traces of drugs. Sometimes, your body can react to one of these substances as if it were harmful. This reaction may release histamine, which makes the blood vessels in your lips swell—a condition called angioedema. One report talked about a case where lip swelling was seen after using certain recreational drugs, suggesting that sometimes the cause isn’t the kiss itself, but something else you were exposed to during a night out. Another case highlighted the localized swelling along the edge of the lips after exposure to a substance. In rare cases, chronic conditions like cheilitis granulomatosa can cause ongoing swelling, but this is less likely to occur suddenly after a kiss. If your swollen lips hurt a lot, come back often, or are accompanied by other symptoms like trouble breathing, please check in with a healthcare professional for further advice.