Published on: 6/12/2025
What are the different types of multiple myeloma?
Multiple myeloma can be classified into different types based on how the bone marrow looks under a microscope and the stage of the disease.
Explanation
Multiple myeloma is a type of cancer that affects plasma cells in the bone marrow. According to the provided references, it can be classified in several ways based on histological and clinical features.
Histologic Classification: This classification is based on how the bone marrow tissue looks under a microscope. The appearance of the cells and the amount of plasma cells present can help determine the type of myeloma.
Staging: Staging refers to how advanced the disease is. It considers factors such as the number of cancerous cells and the extent to which they have spread in the body.
Understanding these classifications helps doctors determine the best treatment options and predict how the disease might progress. The studies highlight the importance of examining bone marrow samples to accurately classify and stage multiple myeloma.
(References)
- Bartl R, Frisch B, Fateh-Moghadam A, Kettner G, Jaeger K, & Sommerfeld W. (1987). Histologic classification and staging of multiple myeloma. A .... American journal of clinical pathology, 3825999.
- Fujino M. (2018). The histopathology of myeloma in the bone marrow. Journal of clinical and experimental hematopathology : JCEH, 29998977.
- Bartl R, Frisch B, Burkhardt R, Fateh-Moghadam A, Mahl G, Gierster P, et al. (1982). Bone marrow histology in myeloma: its importance in .... British journal of haematology, 7104223.
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