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Published on: 10/9/2026

What causes a yeast infection, and why it keeps coming back

Yeast infections are usually caused by an overgrowth of Candida, a fungus that lives naturally in the vagina, triggered by antibiotics, hormonal shifts from pregnancy or birth control, high blood sugar or diabetes, a weakened immune system, and moisture-trapping clothing. Recurrent infections, defined as four or more in a year, often happen because the original infection was never fully cleared, the yeast strain resists common treatments, or an underlying driver like uncontrolled blood sugar, hormone changes, or sexual reinfection keeps feeding the overgrowth. Several other factors can also mimic or worsen symptoms, including bacterial vaginosis, trichomoniasis, and irritation from douching or scented products, so an accurate diagnosis matters. There are several important distinctions and treatment considerations to weigh, so see below to understand more. Because itching, burning, and discharge can point to multiple conditions with very different treatments, guessing wrong can prolong your discomfort, which is why a free, instant, online symptom check is a smart first step to clarify what may be going on and decide whether you need a prescription, a different test, or in-person care.

Last reviewed for medical accuracy: 10/08/2026

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Explanation

What causes a yeast infection, and why it keeps coming back

Yeast infections (most often vaginal candidiasis) occur when Candida, a type of fungus that normally lives in small amounts on skin and in the vagina, grows out of control. Understanding what can cause a yeast infection—and why some infections recur—helps you take steps to prevent discomfort and disruption to daily life.

What can cause a yeast infection

While Candida lives harmlessly in many people, certain factors allow it to multiply and trigger symptoms such as itching, burning and unusual discharge. Common triggers include:

  • Antibiotic use
    Broad-spectrum antibiotics don’t just kill bad bacteria; they can disrupt the healthy bacterial balance that keeps Candida in check.
  • High-sugar diet
    Excessive sugar and simple carbs provide fuel for yeast growth.
  • Hormonal changes
    Pregnancy, birth control pills or hormone therapy can alter vaginal pH, making it easier for yeast to grow.
  • Diabetes
    Uncontrolled blood sugar creates an environment in which yeast thrives.
  • Tight, non-breathable clothing
    Synthetic underwear or tight pants trap heat and moisture, encouraging fungal growth.
  • Douching and scented products
    Douching, scented tampons or feminine sprays can upset the natural balance of bacteria and yeast.
  • Weakened immune system
    Conditions like HIV, certain cancers or long-term steroid use reduce your body’s ability to keep Candida under control.
  • Stress and lack of sleep
    Chronic stress and poor sleep can impair immune function, increasing susceptibility.

By recognizing these risk factors, you can begin to identify what might be setting off your symptoms.

Why yeast infections keep coming back

Recurrent yeast infections—defined as four or more episodes in a year—occur in up to 8% of women of reproductive age. Recurrence can stem from:

  • Incomplete treatment
    Stopping antifungal therapy early, even if symptoms improve, may allow Candida to rebound.
  • Antifungal resistance
    Repeated or prolonged use of over-the-counter antifungals can select for resistant strains.
  • Non-albicans Candida species
    While Candida albicans causes most infections, other species (e.g., C. glabrata) can be harder to treat.
  • Persistent reservoirs
    Candida can linger on skin folds, in the anus or on underwear and towels, leading to rapid reinfection.
  • Underlying health issues
    Uncontrolled diabetes, hormonal imbalances or an undiagnosed immunodeficiency can fuel repeated outbreaks.
  • Partner reinfection
    Though less common, sexual partners can carry yeast on the skin and reintroduce it.
  • Lifestyle factors
    Ongoing use of tight clothing, douching or high-sugar diets continues to create an environment favorable to yeast.

Addressing recurrence often means looking beyond a single treatment course and making targeted changes in lifestyle, clothing, diet and hygiene.

Strategies to reduce recurrence

  1. Complete the full course of treatment
    Whether using prescription or OTC antifungals, follow directions through to the end.
  2. Practice good genital hygiene
    • Wear breathable cotton underwear and loose-fitting clothes
    • Change damp clothing (e.g., swimsuits, workout gear) promptly
    • Avoid douching and scented sprays—plain water and gentle, unscented soap are enough
  3. Manage blood sugar
    If you have diabetes, keeping glucose levels in range reduces yeast overgrowth.
  4. Consider probiotics
    Some studies suggest strains like Lactobacillus rhamnosus and L. reuteri may help restore healthy vaginal flora.
  5. Review medications and hormones
    Talk to your provider about adjusting birth control or hormone therapy if you suspect these contribute.
  6. Clean personal items regularly
    Wash underwear, sleepwear and towels in hot water. Replace any items you suspect may harbor yeast.
  7. Limit added sugars and refined carbs
    A balanced diet lowers the “food” supply for Candida.

Even with perfect prevention, some people remain prone to recurrence. Recognizing early warning signs—itching, burning or changes in discharge—can help you start treatment promptly.

When to seek medical advice

Most yeast infections respond well to standard antifungal treatments. However, you should speak to a doctor if you experience:

  • Symptoms that don’t improve after one week of treatment
  • More than three yeast infections in a year
  • Unusual symptoms, such as fever, chills, nausea or pain during urination
  • Signs of a different infection (e.g., bacterial vaginosis or a sexually transmitted infection)
  • A weakened immune system (e.g., HIV, chemotherapy)

For a quick, confidential check of your symptoms, you might consider doing a free, online symptom check using the doctor approved Ubie Symptom Checker (https://ubiehealth.com/). It can help you decide whether you need to see a healthcare professional right away.

Why seeing a doctor matters

Recurrent or stubborn yeast infections can signal underlying conditions that require professional attention. A doctor can:

  • Order lab tests to identify the specific Candida species and determine resistance
  • Prescribe longer or alternative antifungal regimens
  • Screen for diabetes, hormonal imbalances or immune disorders
  • Advise on lifestyle or medication changes to reduce recurrence risk

Never ignore symptoms that are severe, unusual or life-threatening. If you experience heavy bleeding, severe pelvic pain, high fever or other alarming signs, seek medical care immediately.


Understanding what can cause a yeast infection and the common reasons for recurrence empowers you to take control of your health. With proper treatment, lifestyle adjustments and medical support when needed, most people regain lasting relief. If you face persistent or severe symptoms, be sure to speak to a doctor about the best next steps.

(References)

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  • * Sobel JD. Recurrent vulvovaginal candidiasis. Am J Obstet Gynecol. 2016 Jan;214(1):15-21. doi: 10.1016/j.ajog.2015.06.067. Epub 2015 Jul 9. PMID: 26164695.

  • * Arroyo-Fajardo A, San Juan-Delgado MF, García-Rodríguez J. [Candida glabrata vaginitis: The great ignored?]. Rev Iberoam Micol. 2017 Oct-Dec;34(4):246. doi: 10.1016/j.riam.2017.01.001. Epub 2017 May 31. PMID: 28579083.

  • * Phillips NA. Recurrent Bacterial Vaginosis: A Recurrent Clinical Dilemma. J Womens Health (Larchmt). 2019 Sep;28(9):1179. doi: 10.1089/jwh.2019.7969. PMID: 31509096.

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