What is the difference in how zolpidem and eszopiclone work?

Zolpidem and eszopiclone are both used to help people sleep, but they have some differences in how they work.

Zolpidem

• Mechanism: Zolpidem works by enhancing the activity of a neurotransmitter called GABA. This helps slow down brain activity, making it easier to fall asleep.
• Use: It is primarily used for short-term treatment of sleep problems, like trouble falling asleep.

Eszopiclone

• Mechanism: Similar to zolpidem, eszopiclone also works by affecting GABA. However, it binds to different sites, which might make it work slightly differently.
• Use: It is often used for both falling asleep and staying asleep, and can be used for a longer period of time compared to zolpidem.

Both medications help with sleep but are chosen based on specific sleep issues and how long treatment is needed. For more information, consult a healthcare provider.