Localized Cutaneous Amyloidosis Quiz
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Reviewed By:
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
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Scar formation after the rash
Skin hard on the fingers
Post-inflammatory scarring
Finger skin is hard
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Learn more about Localized cutaneous amyloidosis
Content updated on Sep 20, 2022
What is localized cutaneous amyloidosis?
Localised cutaneous amyloidosis is a condition in which there is accumulation of a protein called amyloid in between the superficial and deeper layer of the skin. The cause is unknown, but could be triggered due to repeated scratching and rubbing of the skin due to other skin conditions.
Symptoms of localized cutaneous amyloidosis
Black/blue/brown spots or moles, on the skin and lining of the mouth
Skin hardening
Multiple areas of skin redness or red spots
Questions your doctor may ask to check for localized cutaneous amyloidosis
Your doctor may ask these questions to diagnose localized cutaneous amyloidosis
Are there black, blue, or brown spots on the skin or elsewhere? (Including moles)
Do you have hardening of the skin?
Do you have multiple areas of skin which are reddened or have red spots?
Treatment for localized cutaneous amyloidosis
Localised cutaneous amyloidosis causes cosmetic defects hence medications are given to treat the patches, which can include oral pills, injections and creams/ ointments.
View the symptoms of Localized cutaneous amyloidosis
Diseases related to Localized cutaneous amyloidosis
References
Weidner T, Illing T, Elsner P. Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review. Am J Clin Dermatol. 2017 Oct;18(5):629-642. doi: 10.1007/s40257-017-0278-9. PMID: 28342017.
https://link.springer.com/article/10.1007/s40257-017-0278-9
Hamie L, Haddad I, Nasser N, Kurban M, Abbas O. Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis on Atypical Clinical Variants. Am J Clin Dermatol. 2021 Sep;22(5):667-680. doi: 10.1007/s40257-021-00620-9. Epub 2021 Jul 21. PMID: 34286474.
https://link.springer.com/article/10.1007/s40257-021-00620-9
Madarkar MS, Koti VR. FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis. Dermatol Pract Concept. 2021 May 20;11(3):e2021057. doi: 10.5826/dpc.1103a57. PMID: 34123561; PMCID: PMC8172053.
https://www.dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp1103a57
Reviewed By:
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
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Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan