Localized Cutaneous Amyloidosis Quiz
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Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
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Skin tightness of the fingers
Scars or marks from the rash/wound
Moles or spots of different colors on skin or lining of the mouth
Hard fingertips
Developed scars or marks where the rashes/wound was previously
Hardening of the skin of the fingers
After the rash healed, there were scars
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Learn more about Localized cutaneous amyloidosis
Content updated on Sep 20, 2022
What is localized cutaneous amyloidosis?
Localized cutaneous amyloidosis is a condition where amyloid protein accumulates between the superficial and deeper layers of the skin. The cause is unknown but may be triggered by repeated scratching and rubbing of the skin due to other skin conditions.
Symptoms of localized cutaneous amyloidosis
Black/blue/brown spots or moles, on the skin and lining of the mouth
Skin hardening
Multiple areas of skin redness or red spots
Questions your doctor may ask to check for localized cutaneous amyloidosis
Your doctor may ask these questions to diagnose localized cutaneous amyloidosis
Are there black, blue, or brown spots on the skin or elsewhere? (Including moles)
Do you have hardening of the skin?
Do you have multiple areas of skin which are reddened or have red spots?
Treatment for localized cutaneous amyloidosis
Localized cutaneous amyloidosis causes cosmetic defects, so medications are given to treat the patches. These can include oral pills, injections, and creams/ointments.
View the symptoms of Localized cutaneous amyloidosis
Diseases related to Localized cutaneous amyloidosis
References
Weidner T, Illing T, Elsner P. Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review. Am J Clin Dermatol. 2017 Oct;18(5):629-642. doi: 10.1007/s40257-017-0278-9. PMID: 28342017.
https://link.springer.com/article/10.1007/s40257-017-0278-9
Hamie L, Haddad I, Nasser N, Kurban M, Abbas O. Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis on Atypical Clinical Variants. Am J Clin Dermatol. 2021 Sep;22(5):667-680. doi: 10.1007/s40257-021-00620-9. Epub 2021 Jul 21. PMID: 34286474.
https://link.springer.com/article/10.1007/s40257-021-00620-9
Madarkar MS, Koti VR. FotoFinder Dermoscopy Analysis and Histopathological Correlation in Primary Localized Cutaneous Amyloidosis. Dermatol Pract Concept. 2021 May 20;11(3):e2021057. doi: 10.5826/dpc.1103a57. PMID: 34123561; PMCID: PMC8172053.
https://www.dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp1103a57
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Reviewed By:
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
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