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Redness of the skin

Skin has moles or spots of different colors

Rashes in areas of friction

Red when exposed to the sun

Red spots on skin

Black, blue, or brown spots on the skin or elsewhere

Rashes over sun-exposed areas

Not seeing your symptoms? No worries!

What is Mastocytosis?

Mastocytosis happens when there are too many mast cells, which are part of the immune system, in the body. It can affect the skin or other body parts. It's usually caused by a non-inherited genetic mutation and affects both genders equally. Mastocytosis attacks can be triggered by skin friction, physical activity, insect bites, stress, alcohol, certain foods, and medications.

Typical Symptoms of Mastocytosis

Diagnostic Questions for Mastocytosis

Your doctor may ask these questions to check for this disease:

  • Is your whole body red?
  • Are there black, blue, or brown spots on your skin? (Including moles)
  • Do you have multiple red areas or spots on your skin?
  • Do you have itchy skin?
  • Does your skin get red from friction or irritation?

Treatment of Mastocytosis

People with mastocytosis should avoid triggers. Treatment options include medications to lessen symptoms or ultraviolet light therapy. Since there's a higher risk of a severe allergic reaction (anaphylactic shock), they should carry an EpiPen (injectable epinephrine).

Reviewed By:

Caroline M. Doan, DO

Caroline M. Doan, DO (Internal Medicine)

Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.

Yuta Sasaoka, MD

Yuta Sasaoka, MD (Pediatrics)

Dr. Sasaoka graduated from the Sapporo Medical University School of Medicine. After working in the Department of Pediatrics at Hakodate Municipal Hospital, the Emergency Center at Hakodate Municipal Hospital, and the Department of Emergency Medicine at Tokyo Metropolitan Children's General Medical Center, he joined the Sapporo Medical University Advanced Emergency Medical Center in April 2020. Dr. Sasaoka is well versed in pediatric emergency medicine, covering a wide range of pediatrics and emergency medicine. He is also a certified AHA-PALS instructor and focuses on pediatric secondary life support education at the Hokkaido Training Site.

From our team of 50+ doctors

Content updated on Mar 31, 2024

Following the Medical Content Editorial Policy

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References