Plasmacytosis Quiz

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Saqib Baig, MD, MS (Respiratory medicine, Critical Care, Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Plasmacytosis

Content updated on Sep 20, 2022

What is plasmacytosis?

Plasmacytosis occurs when there are excessive numbers of plasma cells (part of the immune system) in the body. This can affect not only the skin but other parts of the body. Reddish-brown skin nodules characterize it. The cause is unclear but could be viral. This rare condition is more common amongst Asians.

Symptoms of plasmacytosis

  • Multiple areas of skin redness or red spots

  • Skin redness or red bumpy rashes

Questions your doctor may ask to check for plasmacytosis

Your doctor may ask these questions to diagnose plasmacytosis

  • Do you have multiple areas of skin which are reddened or have red spots?

  • Do you have red skin or red spots on the skin?

Treatment for plasmacytosis

There is no standardized, effective treatment regimen. Various regimens with different drugs to suppress inflammation and/or radiation therapy are usually prescribed.

View the symptoms of Plasmacytosis

  • Red skin


  • LA C, Soyfoo M. Plasmacytosis and nephrotic syndrome revealing Sjögren's syndrome. Arch Rheumatol. 2020 Dec 10;36(2):311-313. doi: 10.46497/ArchRheumatol.2021.8349. PMID: 34527940; PMCID: PMC8418763.

  • Farraj KL, Kaliounji A, Kagolanu D, Khan N. A Rare Case of Extramedullary Plasmacytosis. J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211040657. doi: 10.1177/23247096211040657. PMID: 34407658; PMCID: PMC8381456.

  • Maxfield L, Casale J, Shah M, Muse ME, Baigrie D. Cutaneous Plasmacytosis Associated with Ehrlichiosis in an African-American Patient. J Clin Aesthet Dermatol. 2021 Mar;14(3):24-27. Epub 2021 Mar 1. PMID: 33841612; PMCID: PMC8021406.

  • Jain S, Hede RV, Khopkar US. Cutaneous plasmacytosis with mast cell infiltration. Indian J Dermatol Venereol Leprol. 2020 Jan-Feb;86(1):91-95. doi: 10.4103/ijdvl.IJDVL_716_17. PMID: 30073990.

  • Yamamoto Y, Matsumura M. Cutaneous plasmacytosis: A rare initial presentation of idiopathic multicentric Castleman's disease. Clin Case Rep. 2021 May 4;9(5):e04109. doi: 10.1002/ccr3.4109. PMID: 34026151; PMCID: PMC8122127.

Reviewed By:

Saqib Baig

Saqib Baig, MD, MS (Respiratory medicine, Critical Care, Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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