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Published on: 2/23/2026

Abnormal Pap Smear? The Medical Reality and Your Approved Next Steps

An abnormal Pap smear is common and usually does not mean cancer; most results reflect temporary cell changes from HPV, minor infection or inflammation, or hormonal shifts that often clear on their own. Next steps depend on your age, specific result, HPV status, and screening history, and may include a repeat Pap in 6 to 12 months, HPV testing, or colposcopy; there are several factors to consider, including which results need treatment and which symptoms require urgent care, so see the complete guidance below.

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Explanation

Abnormal Pap Smear? The Medical Reality and Your Approved Next Steps

Hearing that you have an abnormal Pap smear can feel alarming. It's completely normal to worry. But here's the most important thing to understand:

An abnormal Pap smear does not mean you have cancer.

In fact, most abnormal Pap smear results are caused by minor cell changes that either resolve on their own or can be easily monitored and treated. Let's walk through what this result actually means, what causes it, and what you should do next—based on trusted medical guidance.


What Is a Pap Smear?

A Pap smear (also called a Pap test) is a screening test that checks for changes in the cells of the cervix—the lower part of the uterus that opens into the vagina.

The goal of a Pap smear is simple:

  • Detect abnormal cervical cells early
  • Identify precancerous changes before they turn into cancer
  • Reduce the risk of cervical cancer

Thanks to regular Pap smear screening, cervical cancer rates have dropped significantly over the past several decades.


What Does "Abnormal Pap Smear" Actually Mean?

An abnormal Pap smear means that some cervical cells look different from normal under a microscope.

It does not automatically mean:

  • You have cervical cancer
  • You will develop cancer
  • You need immediate treatment

In many cases, the changes are mild and temporary.


Common Causes of an Abnormal Pap Smear

Several things can cause an abnormal Pap smear result:

1. Human Papillomavirus (HPV)

The most common cause.

  • HPV is extremely common.
  • Most sexually active people will have it at some point.
  • In most cases, the immune system clears HPV on its own.
  • Certain high-risk HPV types can lead to cervical cell changes over time.

2. Mild Cervical Cell Changes (Low-Grade Changes)

These often:

  • Resolve without treatment
  • Just require monitoring

3. Inflammation or Infection

Sometimes cell changes are caused by:

  • Yeast infections
  • Bacterial infections
  • Sexually transmitted infections
  • Irritation

If you're noticing unusual discharge, itching, or odor alongside your abnormal Pap result, Ubie's free AI-powered Abnormal vaginal discharge Symptom Checker can help you understand possible causes and whether additional evaluation may be needed.

4. Hormonal Changes

Especially common:

  • After menopause
  • During pregnancy

Types of Abnormal Pap Smear Results

Your healthcare provider may use specific terms. Here's what they typically mean:

ASC-US (Atypical Squamous Cells of Undetermined Significance)

  • The most common abnormal result
  • Mild changes
  • Often related to HPV
  • Usually monitored or followed up with HPV testing

LSIL (Low-Grade Squamous Intraepithelial Lesion)

  • Mild abnormalities
  • Often linked to HPV infection
  • Frequently resolves without treatment

HSIL (High-Grade Squamous Intraepithelial Lesion)

  • More serious cell changes
  • Higher risk of becoming cancer over time
  • Requires further testing and possibly treatment

AGC (Atypical Glandular Cells)

  • Less common
  • May require additional testing

Your provider will explain which category applies to you and what it means.


What Happens Next?

The next steps depend on:

  • Your age
  • The specific abnormal result
  • Whether HPV was detected
  • Your prior Pap smear history

Common follow-up steps include:

1. Repeat Pap Smear

For mild abnormalities, your doctor may recommend:

  • Repeat testing in 6–12 months

This allows time to see if the changes go away naturally.

2. HPV Testing

An HPV test may be done to:

  • Identify high-risk HPV strains
  • Help determine your risk level

3. Colposcopy

If more evaluation is needed, your doctor may recommend a colposcopy.

This is:

  • An in-office procedure
  • Similar to a Pap smear
  • Uses magnification to examine the cervix
  • May include a small biopsy

It sounds intimidating, but most patients tolerate it well.


When Is Treatment Needed?

Treatment is generally only needed for:

  • Persistent high-grade cell changes
  • Biopsy-confirmed precancerous lesions

Treatment options may include:

  • LEEP (Loop Electrosurgical Excision Procedure)
  • Cold knife cone biopsy
  • Other minor surgical procedures

These treatments remove abnormal cells before they can develop into cancer. When caught early, the outcomes are excellent.


How Common Is Cervical Cancer After an Abnormal Pap Smear?

The reassuring truth:

  • Most abnormal Pap smear results never become cancer.
  • Cervical cancer usually develops slowly over many years.
  • Regular screening is highly effective at preventing advanced disease.

The purpose of screening is early detection—so abnormalities can be addressed long before they become dangerous.


Symptoms You Should Not Ignore

Even if you've had an abnormal Pap smear, remember that early cervical cell changes often cause no symptoms.

However, you should speak to a doctor immediately if you experience:

  • Bleeding after sex
  • Bleeding between periods
  • Pelvic pain not related to menstruation
  • Persistent abnormal vaginal discharge
  • Unexplained postmenopausal bleeding

These symptoms don't automatically mean cancer, but they do require medical evaluation.


Emotional Impact: It's Okay to Feel Concerned

An abnormal Pap smear can cause anxiety. That's understandable.

But keep these facts in mind:

  • Most cases are mild.
  • Many resolve on their own.
  • Follow-up care is highly effective.
  • Cervical cancer is largely preventable with proper screening.

Staying informed and following your provider's recommendations gives you control.


How to Protect Your Cervical Health

Here are evidence-based steps to reduce your risk:

  • Stay up to date on Pap smear screenings
  • Follow through with recommended follow-up appointments
  • Consider HPV vaccination if eligible
  • Avoid smoking (smoking increases cervical cancer risk)
  • Practice safe sex

Regular screening remains your most powerful protection.


When to Speak to a Doctor Immediately

You should speak to a doctor promptly if you:

  • Have severe pelvic pain
  • Experience heavy or unusual bleeding
  • Have concerning symptoms that worsen
  • Feel uncertain about your test results

While most abnormal Pap smear results are not life-threatening, any symptoms that feel serious, severe, or persistent should be evaluated by a medical professional without delay.

If you ever feel that something may be urgent or life-threatening, seek immediate medical care.


The Bottom Line

An abnormal Pap smear is common—and in most cases, manageable.

It means:

  • Some cervical cells look different
  • Further monitoring or testing may be needed
  • Cancer is unlikely, especially with follow-up care

The key is not to ignore the result.

Instead:

  • Understand your specific findings
  • Follow your provider's recommendations
  • Keep up with regular screening

Early detection saves lives. And in the vast majority of cases, an abnormal Pap smear is simply a signal to take the next smart, preventive step—not a reason to panic.

If you have questions, concerns, or symptoms, speak to a doctor. Your health deserves clear answers and professional guidance.

(References)

  • * Perkins RB, Guido RS, Castle PE, Conageski C, Huh WK, Kim JJ, Saraiya M, Smith KM, Stier EA, Wentzensen N, Schiffman M, Sawaya GF, Waxman AG. 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J Low Genit Tract Dis. 2020 Apr;24(2):102-131. doi: 10.1097/LGT.0000000000000525. PMID: 32243285. PMCID: PMC7188701.

  • * Fontham ET, Wolf AM, Church TR, Etzioni R, Flowers CR, Garcia R, Guerra C, Gulati R, Jacobson D, Kohlmann S, Levin B, Lim SS, Nead KT, Oeffinger KC, Rosai J, Siegel RL, Smith RA, Wender RC, Saubolle J, Schrag D. American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer. CA Cancer J Clin. 2020 Sep;70(5):347-372. doi: 10.3322/caac.21626. Epub 2020 Aug 13. PMID: 32790100.

  • * Bibbo M, Wilbur D. The 2014 Bethesda System for reporting cervical cytology. Diagn Cytopathol. 2015 May;43(5):355-61. doi: 10.1002/dc.23223. PMID: 25779089.

  • * Maudsley AA, Hillier S, Smith L. Experiences of women referred to colposcopy clinic: a qualitative study of fear, anxiety and feelings of disempowerment. J Psychosom Obstet Gynaecol. 2017 Dec;38(4):307-314. doi: 10.1080/0167482X.2017.1350868. Epub 2017 Aug 1. PMID: 28762744.

  • * Schiffman M, Castle PE. Human papillomavirus: epidemiology and public health. Arch Pathol Lab Med. 2020 Nov 1;144(11):1321-1327. doi: 10.5858/arpa.2020-0435-RA. Epub 2020 Oct 14. PMID: 33052608.

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