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Published on: 2/7/2026

Anemia Over 65: Identifying the Root Cause of Low Energy

Persistent low energy, weakness, or shortness of breath in adults over 65 often points to anemia, which is common but not a normal part of aging. There are several factors to consider, including iron deficiency, low vitamin B12 or folate, anemia of chronic disease or kidney disease, and less commonly bone marrow disorders, and evaluation typically starts with a CBC plus targeted tests. See below for the key warning signs, when to talk with a clinician, how to use a symptom checker, and the cause‑specific treatments that can restore energy, since early evaluation and these details can change the right next steps for you.

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Explanation

Anemia Over 65: Identifying the Root Cause of Low Energy

Feeling tired all the time is often dismissed as "just part of getting older." However, for adults over 65, ongoing fatigue, weakness, or shortness of breath may point to Anemia, a common but often overlooked medical condition. Understanding what Anemia is, why it happens, and how it is evaluated can help you or a loved one take practical steps toward better energy and health.

This guide is based on established medical knowledge from trusted organizations such as national health institutes, geriatric medicine societies, and peer‑reviewed clinical research. It is written in plain language and aims to inform without causing unnecessary worry.


What Is Anemia?

Anemia occurs when your blood does not have enough healthy red blood cells or hemoglobin. Hemoglobin is the protein that carries oxygen from your lungs to the rest of your body. When oxygen delivery drops, your organs and muscles have to work harder, which can lead to low energy and other symptoms.

In adults over 65, Anemia is not rare. Studies show that more than 1 in 10 older adults has some form of Anemia, and the number increases with age. Importantly, Anemia is not considered a normal part of aging—it usually has an underlying cause that deserves attention.


Why Anemia Is More Common After 65

As we age, several factors can increase the risk of Anemia:

  • Changes in nutrient absorption, especially iron, vitamin B12, and folate
  • Chronic medical conditions, such as kidney disease or inflammatory disorders
  • Medications that affect blood production or cause slow blood loss
  • Less obvious bleeding, particularly from the digestive tract

Older adults may also have more than one contributing factor at the same time, which can make Anemia harder to detect without proper testing.


Common Symptoms of Anemia in Older Adults

Symptoms of Anemia can be subtle and may develop slowly. Many people assume they are just "slowing down." Common signs include:

  • Ongoing fatigue or low energy
  • Weakness or feeling easily worn out
  • Shortness of breath during normal activities
  • Dizziness or lightheadedness
  • Pale skin
  • Cold hands or feet
  • Difficulty concentrating
  • Faster or irregular heartbeat

Not everyone experiences all of these symptoms. Some people only notice that everyday tasks feel harder than they used to.


Identifying the Root Causes of Anemia Over 65

Finding the cause of Anemia is essential, because treatment depends on what is driving it. Below are the most common root causes in older adults.

1. Iron Deficiency

Iron deficiency is a leading cause of Anemia. In people over 65, it is often related to:

  • Slow blood loss from the stomach or intestines
  • Poor dietary intake of iron-rich foods
  • Reduced absorption due to stomach or intestinal conditions

Iron deficiency in older adults should always be evaluated carefully, as it can sometimes signal hidden bleeding.


2. Vitamin B12 or Folate Deficiency

Vitamin B12 and folate are essential for red blood cell production. Low levels can result from:

  • Reduced stomach acid, which affects absorption
  • Certain medications
  • Digestive conditions
  • Limited dietary intake

B12 deficiency can also affect the nervous system, sometimes causing numbness, balance issues, or memory changes in addition to Anemia.


3. Anemia of Chronic Disease

Many older adults live with long-term health conditions that can interfere with red blood cell production. These include:

  • Chronic kidney disease
  • Autoimmune or inflammatory disorders
  • Ongoing infections
  • Some cancers

In these cases, Anemia develops as part of the body's response to chronic illness.


4. Kidney-Related Anemia

The kidneys produce a hormone that signals the body to make red blood cells. When kidney function declines, this signal weakens, leading to Anemia. This is common in people with moderate to severe kidney disease.


5. Bone Marrow Disorders

Less commonly, Anemia can be linked to problems within the bone marrow, where blood cells are made. Examples include:

  • Myelodysplastic syndromes
  • Other blood-related conditions

These causes are more complex and usually require evaluation by a specialist.


Why Anemia Should Not Be Ignored

While Anemia itself is often manageable, untreated Anemia can affect quality of life and physical independence. Research has linked Anemia in older adults to:

  • Increased risk of falls
  • Reduced physical stamina
  • Worsening heart conditions
  • Slower recovery from illness or surgery

This does not mean that serious outcomes are inevitable, but it does mean Anemia deserves proper medical attention.


How Anemia Is Evaluated

Diagnosing Anemia usually starts with a simple blood test called a complete blood count (CBC). If Anemia is found, additional tests may be ordered to identify the cause, such as:

  • Iron studies
  • Vitamin B12 and folate levels
  • Kidney function tests
  • In some cases, evaluation of the digestive tract

If you are noticing symptoms and want a starting point, Ubie's free AI-powered Anemia symptom checker can help you understand your symptoms better and prepare for a more informed conversation with your doctor.


Treatment Depends on the Cause

There is no single treatment for Anemia. Management is tailored to the underlying issue and may include:

  • Iron supplements or dietary changes
  • Vitamin B12 injections or oral supplements
  • Treating chronic medical conditions more effectively
  • Adjusting medications
  • Specialized therapies for kidney or bone marrow conditions

Many people experience meaningful improvements in energy once the cause is identified and addressed.


Supporting Energy and Health With Anemia

Alongside medical treatment, general health habits can support recovery:

  • Eating a balanced diet with adequate protein, iron, and vitamins
  • Staying physically active within personal limits
  • Reporting new or worsening symptoms promptly
  • Attending regular medical checkups

These steps do not replace medical care but can work alongside it.


When to Speak to a Doctor

It is important to speak to a doctor if you or a loved one over 65 experiences:

  • Persistent fatigue or weakness
  • Shortness of breath with routine activity
  • Dizziness, fainting, or chest discomfort
  • Rapid or irregular heartbeat
  • Any symptoms that interfere with daily life

Some causes of Anemia can be serious or even life-threatening if left untreated. Early evaluation makes a meaningful difference.


Key Takeaway

Anemia in adults over 65 is common, treatable, and not something to ignore. Low energy may be the body's way of signaling an underlying issue that deserves attention. With proper evaluation, clear communication, and appropriate treatment, many older adults can regain strength, improve daily function, and protect their long-term health.

If you suspect Anemia, use tools like a free online symptom check, and most importantly, speak to a doctor who can guide you through safe and effective next steps.

(References)

  • * Valent P, Cerny-Reiterer S, Gastl G, Theurl I, Stauder R. Anemia in the elderly: what to consider. Semin Hematol. 2017 Apr;54(2):83-92. doi: 10.1053/j.seminhematol.2017.04.004. PMID: 28571861.

  • * Girelli D, Marchi G, Marchi S, Grotto E, Busti F, Poggiana C, Vianello S, Pignatti P, Pavanello M, Tommasi V. Anemia in older adults: A review of prevalence, causes, and management. Front Med (Lausanne). 2018 Dec 19;5:367. doi: 10.3389/fmed.2018.00367. PMID: 30678666; PMCID: PMC6307739.

  • * Bhasin R, Artz AS. Diagnosis and Management of Anemia in Older Adults. Curr Geriatr Rep. 2022;11(3):79-87. doi: 10.1007/s13670-022-00424-6. Epub 2022 Aug 23. PMID: 36021464; PMCID: PMC9401734.

  • * Poggiana C, Marchi G, Marchi S, Girelli D. Iron deficiency and iron deficiency anemia in older adults. Curr Geriatr Rep. 2022;11(3):88-97. doi: 10.1007/s13670-022-00425-5. Epub 2022 Aug 23. PMID: 36021465; PMCID: PMC9401736.

  • * Fuhrmann M, Boivin M, Valent P, Cerny-Reiterer S. Anemia of chronic disease in older adults: current concepts and management. Ann Hematol. 2023 Oct;102(10):2757-2767. doi: 10.1007/s00277-023-05459-x. Epub 2023 Aug 26. PMID: 37628994.

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