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Published on: 2/24/2026
Cracked, sore corners of the mouth are often angular cheilitis, usually caused by saliva-related moisture that allows yeast or bacteria to overgrow, and sometimes linked to irritants, ill-fitting dentures, iron or B vitamin deficiencies, diabetes, or immune problems.
Medically approved steps include protecting the skin with a barrier ointment, using antifungal or antibiotic creams when indicated, and addressing dentures and nutritional or medical issues, with most cases healing in 1 to 2 weeks. There are several factors to consider, so see below for key details on diagnosis, prevention, and when to seek care that could change your next steps.
If you've noticed painful cracks, redness, or sores at the corners of your mouth, you may be dealing with angular cheilitis. It's a common condition, but it can be uncomfortable and frustrating—especially when it keeps coming back.
The good news? In most cases, angular cheilitis is treatable and manageable once you understand what's causing it.
Below, we'll explain what angular cheilitis is, why it happens, how to treat it with medically approved steps, and when you should speak to a doctor.
Angular cheilitis is inflammation that affects one or both corners of the mouth (the angles). It often appears as:
It can make everyday activities—like eating, talking, or smiling—painful.
Unlike cold sores, angular cheilitis is usually not caused by a virus. Instead, it often develops due to irritation combined with fungal or bacterial overgrowth.
Angular cheilitis usually develops when saliva collects in the corners of the mouth. This creates a moist environment where microorganisms—especially Candida (yeast) and certain bacteria—can grow.
Common causes include:
Saliva irritates the skin and breaks down its protective barrier.
When the skin barrier is damaged, these microbes can overgrow and cause inflammation.
Deficiencies in certain nutrients can make you more vulnerable:
If angular cheilitis keeps recurring, a doctor may check for underlying deficiencies.
Some health conditions increase risk:
If you have recurring angular cheilitis, your doctor may investigate underlying causes.
Angular cheilitis can affect anyone, but it's more common in:
Most of the time, a doctor can diagnose angular cheilitis simply by looking at it.
If it doesn't improve with basic treatment, your doctor may:
If you're experiencing symptoms at the corners of your mouth and want to understand whether it could be Angular Cheilitis, a free AI-powered symptom checker can help you identify what might be causing your discomfort in just a few minutes.
Treatment depends on the cause. Here's what healthcare professionals typically recommend:
The first step is reducing moisture and irritation.
This helps the skin heal and prevents further breakdown.
If Candida is suspected, doctors often prescribe:
These are typically applied 2–3 times daily for 1–2 weeks.
Do not stop early—even if it looks better—unless instructed by your doctor.
If bacteria are involved, your doctor may recommend:
Sometimes a combination cream (antifungal + mild steroid) is used for short-term relief of inflammation.
If testing shows deficiencies, treatment may include:
Do not self-prescribe high-dose supplements without medical advice.
If dentures contribute to moisture pooling:
If you have diabetes or another chronic condition:
With proper treatment:
If symptoms persist longer than two weeks, worsen, or keep coming back, you should speak to a doctor.
Yes. Recurrence is common if the underlying cause isn't addressed.
Prevention strategies include:
If angular cheilitis keeps returning, a deeper evaluation may be necessary.
While angular cheilitis is usually not dangerous, you should speak to a doctor if:
These could signal a more serious underlying issue.
If you ever experience symptoms that feel severe, rapidly worsening, or potentially life-threatening, seek urgent medical care immediately.
Understanding what it's not can prevent confusion:
It's usually a combination of moisture, irritation, and infection—not something you "did wrong."
To support healing:
Simple changes often make a big difference.
Angular cheilitis is a common condition that causes cracked, painful corners of the mouth. It's usually due to moisture buildup combined with yeast or bacterial overgrowth—and sometimes nutritional deficiencies or medical conditions.
The good news is that most cases respond well to:
If you're experiencing persistent symptoms and want to better understand what might be happening, using a free Angular Cheilitis symptom checker can provide helpful insights before your next doctor's visit.
And most importantly: if symptoms persist, recur frequently, or are accompanied by other concerning health changes, speak to a doctor. Some underlying causes—like anemia, diabetes, or immune problems—can be serious and deserve proper medical attention.
With the right treatment and a little prevention, angular cheilitis is very manageable—and in most cases, completely treatable.
(References)
* Yang CC, Al-Dabagh A. Angular Cheilitis: Updates in Diagnosis and Management. Am J Clin Dermatol. 2020 Feb;21(1):5-13. doi: 10.1007/s40257-019-00465-3. PMID: 31734892.
* Kulakov AA, Sargsyan KA. Systemic Factors Associated with Angular Cheilitis. Stomatologiia (Mosk). 2023;102(3):10-15. Russian. doi: 10.17116/stomat2023102310. PMID: 37436034.
* Millsop JW, Fazel N. Oral candidosis and angular cheilitis: clinical and diagnostic aspects. Clin Dermatol. 2016 Nov-Dec;34(6):661-665. doi: 10.1016/j.clindermatol.2016.06.012. PMID: 27916301.
* Tarvade S, Ghadge A. Denture stomatitis and angular cheilitis in elderly patients. J Indian Prosthodont Soc. 2018 Jan-Mar;18(1):37-41. doi: 10.4103/jips.jips_185_17. PMID: 29559779; PMCID: PMC5841441.
* Park KK, Kim GW, Lee JH, Kim HS, Ko HC, Kim BS, Kim MB. Angular cheilitis: clinical and aetiological aspects. Ann Dermatol. 2012 Nov;24(4):460-4. doi: 10.5021/ad.2012.24.4.460. Epub 2012 Nov 22. PMID: 23204639; PMCID: PMC3505929.
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