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Published on: 11/20/2025
Can stopping certain antidepressants improve REM Sleep Behavior Disorder (RBD) symptoms?
Stopping certain antidepressants like duloxetine and venlafaxine may help improve REM Sleep Behavior Disorder symptoms.
Wondering why stopping antidepressants affects RBD?
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Antidepressants such as duloxetine and venlafaxine have been linked to causing or worsening REM Sleep Behavior Disorder (RBD). RBD is a condition where people act out their dreams while sleeping, which can sometimes be dangerous.
Research suggests that these medications can trigger RBD symptoms. For example, duloxetine has been shown to induce RBD, and stopping the medication may help reduce these symptoms. Similarly, venlafaxine is another antidepressant that can lead to RBD, and discontinuing it may also relieve symptoms.
However, it is important to note that stopping any medication should be done under the guidance of a healthcare professional. This ensures that the benefits and risks are carefully weighed, and any withdrawal symptoms are managed appropriately.
If you or someone you know is experiencing mental health concerns, please visit 988lifeline.org for support.
(References)
- Tan L, Zhou J, Yang L, Ren R, Zhang Y, Li T, & Tang X. (2017). Duloxetine-induced rapid eye movement sleep behavior .... BMC Psychiatry, 5698922.
- Kierlin L, & Littner MR. (2011). Parasomnias and Antidepressant Therapy: A Review of the .... Frontiers in Psychiatry, 3235766.
- Ryan Williams R, & Sandigo G. (2017). Venlafaxine-induced REM sleep behavioral disorder .... Trauma Case Reports, 5887064.
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