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Published on: 2/10/2026
Appendicitis in women over 65 often presents with subtle, atypical symptoms that are easy to miss, including mild or diffuse belly discomfort, bowel habit changes, nausea without vomiting, urinary urgency, low or no fever, and unexplained fatigue. Because diagnosis can be delayed in this age group, prompt evaluation for persistent or worsening symptoms is important to prevent rupture and serious infection. There are several factors to consider, from medications and other conditions that mask signs to the exact red flags, timelines, tests, and treatments; see below for the complete answer and guidance on what to do next.
Appendicitis is often thought of as a condition that affects younger people, but it can and does occur in older adults—including women over 65. In this age group, appendicitis may look very different from the "classic" symptoms many people expect. Because signs can be subtle or atypical, diagnosis is sometimes delayed, which can increase the risk of complications.
This guide explains what appendicitis is, how it can present differently in women aged 65 and older, and which symptoms should never be ignored. The goal is to inform and empower—not to alarm—so you know when it's time to take action and speak to a doctor.
Appendicitis is inflammation of the appendix, a small pouch attached to the large intestine. When the appendix becomes blocked—by stool, infection, or swelling—it can become inflamed and infected. Without treatment, the appendix can rupture, leading to serious infection in the abdomen.
In older adults, appendicitis is less common than in younger people, but it tends to be more serious when it occurs, largely because symptoms may be missed or mistaken for other conditions.
As we age, the body responds to illness differently. Pain perception changes, immune responses may be weaker, and many older women live with other medical conditions that can mask or mimic appendicitis.
Key reasons appendicitis can be harder to spot after 65 include:
Because of these factors, appendicitis in older women is more likely to be diagnosed later in its course.
Some women over 65 do experience typical appendicitis symptoms, such as:
However, many older women do not experience this classic pattern.
In women aged 65 and older, appendicitis often shows up in quieter, less obvious ways. These symptoms are easy to dismiss but deserve attention.
Instead of sharp pain, you may notice:
This discomfort may not be limited to the lower right side.
Appendicitis can affect digestion, leading to:
These changes may be mistaken for dietary issues or irritable bowel symptoms.
A low-level infection can cause:
This is sometimes the only early sign in older adults.
Older women with appendicitis may feel:
Vomiting may never occur, which can make the problem seem less serious than it is.
Unlike younger patients, women over 65 may have:
This does not rule out appendicitis.
Because of the appendix's location, inflammation can irritate the bladder, causing:
These symptoms can be mistaken for a urinary tract infection.
In women over 65, appendicitis is more likely to:
Prompt evaluation greatly reduces these risks. Listening to subtle body changes and acting early can make a significant difference.
You should not ignore symptoms if you notice:
If you're concerned about any combination of these symptoms and want to better understand what they might mean, consider using a free Acute Appendicitis symptom checker to help you determine whether you should seek urgent medical care—but remember this should never replace a professional evaluation by your doctor.
Doctors use several tools to diagnose appendicitis, including:
Because symptoms may be unclear, imaging is especially important in women over 65.
Treatment depends on how early appendicitis is found.
Your doctor will recommend the safest and most effective option based on your overall health and the severity of inflammation.
Older women sometimes delay care because symptoms don't seem "bad enough." It's important to trust your instincts.
Helpful steps include:
You know your body best.
Appendicitis in women aged 65 and older often whispers instead of shouts. The signs may be subtle, but the condition is serious if left untreated. Paying attention to small changes and acting early can prevent complications and support better outcomes.
If you notice symptoms that concern you—or if something simply doesn't feel right—speak to a doctor as soon as possible, especially about anything that could be life-threatening or serious. Getting medical advice promptly is not overreacting; it's a smart and responsible step toward protecting your health.
(References)
* Yu CW, Huang CW, Lin KC, Wang YC, Cheng CY, Chang YT, Lee CC. Acute appendicitis in the elderly: a diagnostic challenge. Ulus Travma Acil Cerrahi Derg. 2013 Nov;19(6):528-32. PMID: 24272183.
* Podda M, Evola S, Formisano G, Loi F, Micali G, Mura G, Melis L, Pisanu A. Acute appendicitis in the geriatric population: a systematic review. Int J Surg. 2021 Mar;87:105869. PMID: 33549725.
* Almaramhi T, Balakrishnan K, Raftery G, Lawton J, Sanyal S. Challenges in the diagnosis of appendicitis in older adults: A systematic review. Ann Med Surg (Lond). 2024 Mar 12;86:2324-2330. PMID: 38487192.
* Liu K, Wang Z, Zhao P, Yan J, Peng Y, Song J. Acute appendicitis in the elderly: A retrospective cohort study. Medicine (Baltimore). 2017 Jul;96(27):e7381. PMID: 28684705.
* Al-Ghaithi B, O'Neill S, Coffey JC. Acute Appendicitis in the Elderly: A Retrospective Analysis. Cureus. 2023 Dec 16;15(12):e50588. PMID: 38222378.
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