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Published on: 7/14/2026
Yes, armpit pain years after a mastectomy is common and can occur for several reasons. Known as post-mastectomy pain syndrome (PMPS), this lingering discomfort may stem from nerve damage, scar tissue, lymph node changes, or muscle strain following surgery. Each person's experience is unique, and symptoms can range from mild tenderness to sharp, burning, or shooting pain.
Understanding the underlying cause is the first step toward relief. Because armpit pain can also signal unrelated conditions—such as infections, cysts, or musculoskeletal issues—it's important not to assume every ache is surgery-related. Getting clarity quickly helps you decide whether to try at-home care, contact your oncologist, or seek further evaluation. Take a free, instant, online symptom check to better understand what may be causing your pain and confidently plan your next steps.
Reviewed for medical accuracy: 07/14/2026
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Submit your own QuestionAfter a mastectomy, some people experience persistent pain that can include discomfort in the armpit area. Researchers have looked into why this happens and found that the pain can sometimes be linked to changes in the nerves, scar tissue formation, or even swelling related to changes in the lymph system. Studies have shown that even when doctors cannot pinpoint an exact treatment factor causing the pain, many patients continue to feel discomfort long after their surgery. This persistent pain is sometimes called "post-mastectomy pain syndrome." It is important to remember that while it can be normal to have some discomfort for a long time, any new pain patterns or concerns should be shared with a doctor or a healthcare provider. If you're experiencing symptoms and want to better understand what might be causing your discomfort, you can start by taking our free symptom checker before your appointment. If you feel your pain is managed poorly, it is also important to see a doctor for help. They can help decide if the pain is a normal part of healing, if it is nerve-related, or if there are other causes that might need treatment or management.
(References)
Bell RJ, Robinson PJ, Nazeem F, Panjari M, Fradkin P, Schwarz M, Davis SR. Persistent breast pain 5 years after treatment of invasive breast cancer is largely unexplained by factors associated with treatment. J Cancer Surviv. 2014 Mar;8(1):1-8. doi: 10.1007/s11764-013-0306-6. Epub 2013 Aug 23. PMID: 23975613.
Gärtner R, Jensen M, Nielsen J, Ewertz M, Kroman N, Kehlet H. Prevalence of and Factors Associated With Persistent Pain Following Breast Cancer Surgery. JAMA. 2009;302(18):1985–1992. doi:10.1001/jama.2009.1568
Tait RC, Zoberi K, Ferguson M, Levenhagen K, Luebbert RA, Rowland K, Salsich GB, Herndon C. Persistent Post-Mastectomy Pain: Risk Factors and Current Approaches to Treatment. J Pain. 2018 Dec;19(12):1367-1383. doi: 10.1016/j.jpain.2018.06.002. Epub 2018 Jun 30. PMID: 29966772; PMCID: PMC6530598.
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