Published on: 3/5/2025
Random sharp pain in the armpit might come from several causes, including issues with lymph nodes or nerve irritation. It can be a signal worth checking with a doctor if it continues or worsens.
Sharp pain in your armpit can happen for different reasons. One possibility involves adenopathy, where lymph nodes become swollen or irritated. Lymph nodes can react to infections, injuries, or other stresses in the body, and this can cause a sudden, sharp pain. In some cases, pain in the armpit can be a sign of something more serious, like a problem involving the nerves that come from the upper part of the chest or neck. One study noted that axillary pain (pain in the armpit) can sometimes be an early warning sign of neoplasms (abnormal growths). There are rare cases where sharp pain has been linked to conditions like Hodgkin lymphoma, where unusual lymph node involvement may occur. However, most times, such pain can also be due to minor issues like muscle strain or even changes in nerve movement. Since there are various possible causes, it’s important to speak with a healthcare provider if the pain persists or if you notice other symptoms. They can help find the exact cause and decide the best next steps for you.
(References)
Maini R, Nagalli S. Adenopathy. [Updated 2023 Aug 8]. In: StatPearls [Internet].
Rubin DI, Shuster EA. Axillary pain as a heralding sign of neoplasm involving the upper thoracic root. Neurology. 2006 Jun 13;66(11):1760-2. doi: 10.1212/01.wnl.0000218165.93659.6c. PMID: 16769959.
Yardimci VH, Yardimci AH. An Unusual First Manifestation of Hodgkin Lymphoma: Epitrochlear Lymph Node İnvolvement-A Case Report and Brief Review of Literature. J Investig Med High Impact Case Rep. 2017 Apr 27;5(2):2324709617706709. doi: 10.1177/2324709617706709. PMID: 28508005; PMCID: PMC5415053.
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