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Published on: 2/15/2026
For women in their 40s and 50s, Ashwagandha may gently lower stress, improve sleep, and support mild anxiety, with benefits generally modest and research using standardized extracts at about 300 to 600 mg daily over 6 to 8 weeks; there are several factors to consider, so see below to understand more. Safety and fit depend on your health and medications, especially with thyroid disease, autoimmune conditions, pregnancy, liver issues, or use of sedatives or thyroid medication, and it is not a cure-all; for personalized next steps, including product selection, lifestyle supports, when to seek care, and a menopause symptom check to review with your clinician, see the complete details below.
If you're in your 40s or 50s and feeling more tense, wired, or emotionally stretched than usual, you're not alone. Hormonal shifts during perimenopause and menopause can affect sleep, mood, and your ability to unwind. Many women are looking for natural ways to support calm and resilience.
One option that's gained attention is Ashwagandha for relaxation. But what does the science really say? Is it safe? And is it right for you?
Here's what you need to know.
Ashwagandha (Withania somnifera) is an herb used in traditional Ayurvedic medicine for centuries. It's often described as an "adaptogen," meaning it may help the body respond more effectively to stress.
Modern research suggests Ashwagandha may help regulate cortisol, the body's primary stress hormone. Cortisol plays a key role in:
During perimenopause and menopause, fluctuating estrogen and progesterone can disrupt this balance, sometimes amplifying stress responses. That's why many women are exploring Ashwagandha for relaxation during this stage of life.
Hormonal shifts during this time can bring:
Research from randomized controlled trials suggests Ashwagandha may:
Some studies in adults with chronic stress have shown significant reductions in stress and anxiety scores after 6–8 weeks of daily supplementation. Other studies show improved sleep and faster sleep onset.
While these studies are promising, most are small to moderate in size. Ashwagandha is not a cure-all, but it may be a helpful tool in a broader stress-management plan.
Ashwagandha appears to support relaxation through several mechanisms:
For women in midlife, stress can feel amplified because hormonal changes affect the brain's stress circuitry. Supporting that system can make everyday challenges feel more manageable.
Clinical research suggests:
However:
Ashwagandha for relaxation is best viewed as supportive—not a replacement for medical treatment when needed.
For most healthy adults, Ashwagandha is considered relatively safe when used appropriately. But it is not right for everyone.
You should avoid or use caution if you:
Rare cases of liver injury have been reported with herbal supplements, including Ashwagandha. This is uncommon but important to know.
Always speak to a doctor before starting any supplement, especially if you have medical conditions or take prescription medications.
It's important to stay realistic.
Ashwagandha for relaxation:
If your symptoms are intense, worsening, or interfering with daily life, they deserve proper evaluation.
Midlife symptoms can overlap. What feels like "stress" may actually be:
If you're experiencing symptoms like mood swings, sleep disruptions, or anxiety and want to understand whether hormonal changes may be playing a role, Ubie's free AI-powered Peri-/Post-Menopausal Symptoms checker can help you identify patterns and provide personalized insights in just a few minutes—making it easier to have an informed conversation with your doctor.
If you and your healthcare provider decide it's appropriate, consider the following:
Look for products standardized to withanolides (the active compounds), often around 5%.
Follow label instructions and medical guidance.
Most studies show benefits after 6–8 weeks. This is not an immediate calming agent like a sedative.
Watch for:
Stop and speak to a doctor if concerning symptoms develop.
Ashwagandha works best as part of a larger plan. Evidence-based strategies that complement it include:
These lifestyle foundations often have effects equal to—or greater than—supplements alone.
In your 40s and 50s, estrogen fluctuations can:
If symptoms are significant, hormone therapy (for appropriate candidates) may be more effective than supplements alone.
Ashwagandha for relaxation can be part of the picture—but it should not delay proper evaluation if symptoms are severe.
Speak to a doctor urgently if you experience:
Stress is common. Serious medical conditions are less common—but they do occur. Don't ignore persistent or intense symptoms.
For many women in their 40s and 50s, Ashwagandha for relaxation may:
It is not a miracle herb. But when used thoughtfully—and under medical guidance—it may be a helpful addition to your wellness plan.
If you're noticing changes in how you handle stress, sleep, or mood, it may help to check whether Peri-/Post-Menopausal Symptoms could be contributing—Ubie's free tool takes just minutes and gives you clarity before your next doctor's appointment.
Most importantly, speak to a doctor before starting Ashwagandha or any supplement—especially if you have underlying health conditions or take medications. And seek medical care right away for any symptoms that feel severe, sudden, or life-threatening.
You deserve support, clarity, and calm during this stage of life. Ashwagandha may be one tool—but the right plan is the one built around your unique health needs.
(References)
* Choudhary, D., Bhattacharyya, S., & Joshi, K. (2023). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for the Management of Anxiety and Stress: A Randomized, Double-Blind, Placebo-Controlled Study. *Cureus*, *15*(6), e37517. PMID: 37375684.
* Lopresti, A. L., Smith, S. J., Malouf, H., & Shorney, S. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. *Medicine (Baltimore)*, *98*(37), e17186. PMID: 31517876.
* Chandrasekhar, K., Kapoor, J., & Anishetty, A. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. *Indian Journal of Psychological Medicine*, *34*(3), 255–262. PMID: 23439798.
* Choudhary, D., Bhattacharyya, S., & Bose, S. (2020). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Modulating Cognitive Functions and Improving Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Study. *Journal of Clinical Pharmacology*, *60*(7), 990–1000. PMID: 32274191.
* Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. *Cureus*, *11*(12), e6466. PMID: 31921764.
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