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Published on: 2/11/2026

Benzonatate: A Woman’s Guide to Relief & Crucial Next Steps

Benzonatate is a non-narcotic cough suppressant that numbs airway receptors to quickly ease persistent cough within 15 to 20 minutes for 3 to 8 hours, but it treats symptoms only and must be swallowed whole. There are several factors to consider; below you will find crucial details on pregnancy and breastfeeding safety, child ingestion risks, side effects and interactions, when to seek urgent care, typical dosing, and supportive home measures that could change your next steps.

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Explanation

Benzonatate: A Woman's Guide to Relief & Crucial Next Steps

If you've been prescribed benzonatate, you're likely dealing with a persistent, uncomfortable cough. Whether it's from a cold, bronchitis, or another respiratory illness, coughing can disrupt sleep, strain your chest, and make daily life exhausting.

This guide explains what benzonatate is, how it works, when it's helpful, what women should know specifically, and when it's time to seek further care.


What Is Benzonatate?

Benzonatate is a non-narcotic prescription medication used to relieve cough. It is commonly sold under the brand name Tessalon® and comes in capsule form.

Unlike many over-the-counter cough medicines that act on the brain's cough center, benzonatate works by numbing the stretch receptors in your lungs and airways. These receptors normally trigger the cough reflex when irritated. By calming them down, benzonatate reduces the urge to cough.

It's typically prescribed for coughs caused by:

  • The common cold
  • Influenza (flu)
  • Bronchitis
  • Pneumonia
  • Other respiratory infections

It is not a cure for the underlying illness. It simply reduces the cough reflex so you can rest and recover more comfortably.


How Benzonatate Works

When you swallow a benzonatate capsule:

  • It is absorbed into your bloodstream.
  • It acts locally on the respiratory tract.
  • It numbs the nerves responsible for triggering coughing.

Most people notice relief within 15 to 20 minutes, and the effect can last for 3 to 8 hours.

It's important to swallow the capsules whole. Do not chew, crush, or dissolve them in your mouth. Doing so can numb your mouth and throat, increasing the risk of choking.


Why Cough Relief Matters

Coughing is a protective reflex, but constant coughing can:

  • Interfere with sleep
  • Cause chest and rib pain
  • Lead to headaches
  • Trigger urinary leakage (especially in women who've had children)
  • Worsen fatigue

For women managing work, caregiving, and daily responsibilities, persistent coughing can significantly impact quality of life. That's where benzonatate can be helpful.


Important Safety Information for Women

While benzonatate is generally safe when used correctly, there are specific considerations women should keep in mind.

Pregnancy

There is limited research on benzonatate use in pregnancy. It is typically prescribed only if clearly needed.

If you are:

  • Pregnant
  • Trying to conceive
  • Unsure if you might be pregnant

Speak with your healthcare provider before taking it.

Breastfeeding

It is not well known whether benzonatate passes into breast milk. If you're breastfeeding, consult your doctor to weigh the risks and benefits.

Accidental Ingestion Risk

Benzonatate capsules can look like candy. Accidental ingestion—especially in children—can be dangerous and potentially life-threatening. Always:

  • Store out of reach of children
  • Keep in original container
  • Never share your prescription

Possible Side Effects

Most women tolerate benzonatate well, but side effects can occur.

Common (Usually Mild)

  • Drowsiness
  • Dizziness
  • Headache
  • Nausea
  • Constipation

Less Common but Serious

  • Confusion
  • Hallucinations
  • Severe drowsiness
  • Allergic reactions (rash, itching, swelling)
  • Chest numbness
  • Trouble breathing

If you experience:

  • Difficulty breathing
  • Severe confusion
  • Swelling of the face or throat
  • Fainting

Seek emergency medical care immediately.


When Benzonatate Is Not Enough

A cough can be a symptom of something minor—or something more serious.

Contact a healthcare provider if your cough:

  • Lasts more than 3 weeks
  • Produces thick green, yellow, or bloody mucus
  • Comes with high fever
  • Causes chest pain
  • Is accompanied by shortness of breath
  • Wakes you gasping for air

If you're concerned your symptoms could be related to something more serious like Pneumonia (Lower Respiratory Tract Infection), a free AI-powered symptom checker can help you understand whether you should seek immediate medical attention.

Pneumonia can sometimes start like a regular cold but worsen over time. Early evaluation matters.


What Benzonatate Does NOT Treat

It's important to understand that benzonatate does not:

  • Kill bacteria
  • Treat viral infections
  • Reduce inflammation
  • Break up mucus
  • Shorten the duration of illness

If your cough is due to:

  • Bacterial pneumonia
  • Severe asthma
  • COVID-19
  • Chronic lung disease

You may need additional treatment.

Always follow your doctor's full treatment plan.


How to Take Benzonatate Safely

To get the most benefit from benzonatate:

  • Take exactly as prescribed.
  • Swallow capsules whole.
  • Do not exceed the recommended dose.
  • Avoid alcohol, which may increase drowsiness.
  • Do not combine with other sedating medications unless approved.

Typical adult dosing ranges from 100 mg to 200 mg up to three times daily, but follow your provider's instructions carefully.

Taking too much can be dangerous. Overdose symptoms may include:

  • Restlessness
  • Tremors
  • Seizures
  • Irregular heartbeat
  • Cardiac arrest

If overdose is suspected, seek emergency care immediately.


Benzonatate vs. Other Cough Medicines

You may wonder how benzonatate compares to other treatments.

Compared to Codeine

  • Benzonatate is non-opioid.
  • It does not carry the same risk of dependence.
  • It typically causes less constipation.

Compared to Dextromethorphan

  • Both suppress cough.
  • Benzonatate works peripherally (in the lungs).
  • Dextromethorphan works centrally (in the brain).

Your doctor chooses based on your specific symptoms and health history.


When to Speak to a Doctor

While many coughs are mild, some situations require prompt medical attention.

Speak to a doctor immediately if you have:

  • Shortness of breath
  • Chest pain or pressure
  • Bluish lips or fingertips
  • Persistent high fever
  • Confusion
  • Rapid breathing
  • A weakened immune system

Even if symptoms seem mild, trust your instincts. If something feels "off," it's worth checking.


Practical Tips for Relief Alongside Benzonatate

Medication is only one part of recovery. You can also:

  • Stay well hydrated (fluids thin mucus)
  • Use a humidifier
  • Get adequate rest
  • Avoid smoke and strong fragrances
  • Elevate your head while sleeping

These supportive steps can improve comfort and healing.


The Bottom Line

Benzonatate can be an effective, non-narcotic option for controlling persistent cough. For many women, it offers much-needed relief, especially when coughing disrupts sleep, work, or caregiving responsibilities.

However, it's important to remember:

  • It treats the symptom—not the cause.
  • It must be taken exactly as prescribed.
  • Serious symptoms should never be ignored.

If your cough worsens, lingers, or is accompanied by concerning symptoms, you can use a free online symptom checker for Pneumonia (Lower Respiratory Tract Infection) to help determine your next steps and speak to a healthcare professional.

Most importantly, always talk to a doctor about any symptoms that could be serious or life-threatening. Early medical evaluation can make a significant difference in outcomes.

Relief matters—but so does knowing when to take the next step.

(References)

  • * Esposito EC, Wampler MA, Davis BD. Benzonatate in the management of cough: a comprehensive review. Expert Opin Drug Metab Toxicol. 2021 Jan;17(1):1-8. doi: 10.1080/17425255.2021.1856717. Epub 2020 Dec 8. PMID: 33261543.

  • * Shirley AA, Goldberg SD. Tessalon Perles (Benzonatate) Toxicity: A Systematic Review. Cureus. 2023 Apr 19;15(4):e37860. doi: 10.7759/cureus.37860. PMID: 37213459; PMCID: PMC10197775.

  • * Kao DK, Ho CS. Pharmacotherapy for upper respiratory tract infections in pregnancy and lactation. J Matern Fetal Neonatal Med. 2018 Jul;31(15):1993-2000. doi: 10.1080/14767058.2017.1350172. Epub 2017 Jul 27. PMID: 28669229.

  • * Kardash J, Kim K. Clinical efficacy and safety of benzonatate for cough: a systematic review. J Fam Pract. 2019 Oct;68(10):579-583. PMID: 31697693.

  • * Mihai A, Naddell E, Goodman SH. Benzonatate Overdose: A Case Report and Review of the Literature. J Med Cases. 2017 Mar;8(3):94-96. doi: 10.14740/jmc2766w. Epub 2017 Mar 23. PMID: 33318287; PMCID: PMC7728257.

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