Our Services
Medical Information
Helpful Resources
Published on: 1/29/2026
There are several factors to consider. See below to understand more. Blood in stool with fatigue in women can be IBD such as ulcerative colitis or Crohn’s, but it also occurs with hemorrhoids or fissures, infections, iron-deficiency anemia, celiac disease, endometriosis, colon polyps, or colorectal cancer; persistent bleeding, worsening tiredness, dizziness, severe abdominal pain, fever, or a family history should prompt timely medical evaluation with blood and stool tests and possibly colonoscopy, with key details on next steps outlined below.
Seeing Blood in Stool can be alarming, especially when it's paired with ongoing fatigue. Many women wonder whether this combination points to inflammatory bowel disease (IBD) or something less serious. The short answer is: it could be IBD, but there are several other possible causes, some mild and some more serious. Understanding what these symptoms may mean—and when to seek care—can help you take the next right step without unnecessary panic.
Blood in Stool refers to visible blood in or on bowel movements, or blood that's only detected through testing. It can look different depending on the source:
Blood may appear:
Fatigue is a common but often overlooked symptom. When Blood in Stool happens repeatedly, even in small amounts, it can lead to iron-deficiency anemia. This is particularly relevant for females, who may already be at higher risk due to menstruation.
Fatigue related to digestive issues may come from:
If fatigue persists for weeks or worsens, it deserves medical attention.
Inflammatory bowel disease (IBD) is a term for chronic conditions that cause inflammation in the digestive tract. The two main types are:
Women with IBD may experience:
IBD often develops gradually and may flare up and calm down over time. It's not caused by stress, though stress can worsen symptoms.
While IBD is one possibility, many other conditions can cause Blood in Stool, fatigue, or both. These include:
This is why persistent or unexplained Blood in Stool should never be ignored, even if you feel otherwise well.
Try not to panic—but do take action if you notice any of the following:
These are reasons to speak to a doctor promptly, as they may signal a serious or life-threatening condition.
A healthcare professional will usually start with a detailed history and physical exam. They may ask about:
These tests help determine whether IBD is present or if another cause explains your symptoms.
If IBD is confirmed, treatment focuses on reducing inflammation, managing symptoms, and preventing complications. Options may include:
Many women with IBD live full, active lives with proper care and monitoring.
If you're experiencing these symptoms and want to better understand what might be causing them, Ubie's free AI-powered blood in stool symptom checker can help you assess your situation and determine how urgently you should seek medical care. It takes just a few minutes and provides personalized guidance based on your specific symptoms.
If you notice Blood in Stool, especially when combined with fatigue or other symptoms, speak to a doctor. Anything that could be serious or life-threatening deserves timely medical attention. Taking action doesn't mean assuming the worst—it means taking your health seriously.
(References)
* Singh S, et al. Fatigue in inflammatory bowel disease: a narrative review. Therap Adv Gastroenterol. 2022 Feb 7;15:17562848221074718. doi: 10.1177/17562848221074718. PMID: 35149303.
* Koutroubakis IE, et al. Iron deficiency anemia in inflammatory bowel disease. Ann Gastroenterol. 2020 Jul-Aug;33(4):347-357. doi: 10.20524/aog.2020.0494. Epub 2020 May 29. PMID: 32679267.
* Ungaro R, et al. Diagnosis and management of inflammatory bowel disease: A clinical review. JAMA. 2022 May 3;327(17):1706-1721. doi: 10.1001/jama.2022.4290. PMID: 35500057.
* Segev L, et al. Sex differences in inflammatory bowel disease. Therap Adv Gastroenterol. 2021 Jun 17;14:17562848211026047. doi: 10.1177/17562848211026047. PMID: 34164821.
* Abraham BP. Inflammatory bowel disease: diagnosis and clinical management. J Am Osteopath Assoc. 2021 Sep 1;121(9):781-792. doi: 10.1515/jaoa-2021-0027. PMID: 34484558.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.