Published on: 6/20/2025
What blood tests are used to diagnose myasthenia gravis?
Blood tests for diagnosing myasthenia gravis look for specific antibodies that attack parts of the muscles and nerves.
Explanation
To diagnose myasthenia gravis, doctors often use blood tests to find certain antibodies. These antibodies can attack parts of the muscles and nerves, making it hard for the body to move properly.
Main Tests:
- Acetylcholine Receptor Antibodies (AChR): This is the most common test. It checks for antibodies that attack the acetylcholine receptors, which are important for muscle movement.
- Muscle-Specific Kinase (MuSK) Antibodies: If the AChR test is negative, doctors might look for MuSK antibodies. These are found in some people with myasthenia gravis, especially when AChR antibodies are not present.
Why These Tests Matter:
- Identifying these antibodies helps doctors confirm if someone has myasthenia gravis.
- Knowing which antibodies are present can guide treatment decisions.
These tests are important because they help doctors figure out if someone has myasthenia gravis and how to best treat it. Each test looks for different antibodies, which can give clues about the condition.
(References)
- Zisimopoulou P, Brenner T, Trakas N, & Tzartos SJ. (2013). Serological diagnostics in myasthenia gravis based on .... Autoimmunity reviews, 23537507.
- Mousavi A, Kumar P, & Frykman H. (2024). The changing landscape of autoantibody testing in .... Clinical biochemistry, 39357636.
- Leite MI, Waters P, & Vincent A. (2010). Diagnostic use of autoantibodies in myasthenia gravis. Autoimmunity, 20380582.
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