Published on: 4/28/2025
A whole body tingling sensation might be caused by nerve problems like peripheral neuropathy, which can result from conditions such as diabetes or kidney issues, vitamin deficiencies, chemical exposure, and it is diagnosed with a careful exam and tests that check how well your nerves work.
Tingling all over the body can be a sign that your nerves are not working the way they should. One common cause is peripheral neuropathy, a condition where the nerves are damaged or irritated. This can come from high blood sugar in diabetes or from waste buildup in the blood seen in kidney problems (uremic neuropathy). Another possibility is small-fiber neuropathy, which affects the tiny fibers that transmit sensations like touch and temperature. Your doctor will start by asking about your symptoms and doing a physical exam to see how you feel. They may also order tests such as nerve conduction studies or electromyography to check your nerve signals. Sometimes, a skin biopsy or blood tests are done to help find out if there’s an underlying condition affecting your nerves. This careful evaluation helps doctors decide on the best treatment to manage or improve your symptoms. If you experience tingling all over your body, it is important to talk to a healthcare provider for proper diagnosis and guidance.
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Pereira MP, Derichs L, Meyer Zu Hörste G, Agelopoulos K, Ständer S. Generalized chronic itch induced by small-fibre neuropathy: clinical profile and proposed diagnostic criteria. J Eur Acad Dermatol Venereol. 2020 Aug;34(8):1795-1802. doi: 10.1111/jdv.16151. Epub 2020 Jan 14. PMID: 31838774.
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