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Published on: 2/23/2026
This guide explains why your face can react after Botox, covering common and temporary effects like redness or swelling, headache, an expressionless look, drooping eyelid, or an uneven smile, and the rare symptoms that require urgent care, with most mild issues resolving in days to weeks. There are several factors to consider. See below for timelines, prevention tips, and the exact next steps, including when to contact your injector, how to monitor symptoms, and when to seek emergency help for breathing or swallowing trouble, vision changes, or severe weakness.
Botox is one of the most widely used cosmetic treatments in the world. It's also used medically for migraines, muscle spasms, excessive sweating, and other conditions. When performed by a qualified professional, botox is generally safe and effective. But like any medical treatment, it can cause side effects.
If your face looks or feels different after botox, you're not alone. Understanding why your face reacts—and what to do next—can help you stay calm, informed, and in control.
Botox is a purified form of botulinum toxin type A. It works by temporarily blocking nerve signals to muscles. When the muscle can't contract as strongly, wrinkles soften and facial lines relax.
The effects are temporary. Most cosmetic results last 3 to 4 months.
Because botox affects muscles and nerves, side effects usually relate to how those muscles respond.
Most side effects are mild and temporary. According to large clinical studies and FDA safety data, common reactions include:
These symptoms usually resolve within a few days.
Botox is injected into muscle tissue. Even with perfect technique, the needle can irritate small blood vessels and nerves. Your body may also briefly react to the medication itself before adjusting.
An overly smooth or expressionless appearance is one of the most talked-about botox side effects.
This happens when:
Botox doesn't know the difference between a wrinkle-causing movement and a natural facial expression. If the injection affects muscles responsible for emotional expression, your face may look flat or less animated.
If you're noticing reduced facial movement or emotion and want to understand whether your symptoms align with this reaction, you can use a free expressionless face symptom checker to explore potential causes and determine if you should seek medical attention.
The good news: this effect is temporary. As the medication wears off, muscle movement gradually returns.
A drooping eyelid is one of the more noticeable botox complications. It happens in a small percentage of patients.
Symptoms usually appear within 3 to 7 days after injection.
While distressing, ptosis is typically temporary and improves within 3 to 6 weeks. Doctors can prescribe eyedrops that help stimulate eyelid muscles during recovery.
If botox is injected around the mouth or cheeks, it can sometimes affect nearby muscles.
You might notice:
This happens when the medication diffuses into muscles responsible for lip control. Again, this is temporary, but it may take several weeks to fully resolve.
Some people experience headaches after cosmetic botox. Ironically, botox is also FDA-approved to treat chronic migraines.
Post-injection headaches may result from:
Most headaches resolve within a few days. Persistent or worsening pain should be discussed with your doctor.
Although uncommon, serious complications can occur. The FDA includes a boxed warning about toxin spread beyond the injection site.
Seek medical attention immediately if you experience:
These symptoms are rare but potentially life-threatening. They require urgent medical care.
True allergic reactions are uncommon but possible.
Warning signs include:
Call emergency services immediately if you suspect a severe allergic reaction.
Every face is different. Botox outcomes depend on:
Some people metabolize botox faster and see minimal side effects. Others are more sensitive and experience stronger reactions.
Choosing a skilled, board-certified medical professional significantly reduces the risk of complications.
Most botox side effects improve within:
Botox is not permanent. Even unwanted results fade over time.
If you notice unexpected changes after botox:
Most reactions are temporary.
They can assess whether what you're experiencing is normal healing or something that needs treatment.
Track:
If you develop breathing problems, swallowing difficulty, or significant weakness, seek emergency medical help immediately.
While no treatment is risk-free, you can reduce risk by:
Honest communication about your medical history is also important. Certain neuromuscular conditions may increase risk.
You should speak to a doctor if:
Even if symptoms seem mild, professional guidance is always appropriate. Never ignore signs that feel unusual or severe.
Botox is widely used and generally safe when administered correctly. Most side effects are mild and temporary. However, because botox affects muscles and nerves, changes in facial movement can happen.
An expressionless face, drooping eyelid, uneven smile, or mild headache may feel alarming—but they usually resolve with time.
That said, serious complications, though rare, require immediate medical attention. Always take breathing, swallowing, or widespread weakness symptoms seriously.
If you're unsure whether what you're experiencing is normal, consider using a symptom assessment tool and speak directly with a healthcare professional.
Your face is important. Your health is more important. When in doubt, speak to a doctor—especially if symptoms could be serious or life threatening.
(References)
* Tzeng SY, Huang YC, Chen RF, Huang CL, Tseng SH. Adverse Events of Botulinum Neurotoxin Type A and Its Management. Toxins (Basel). 2023 Apr 1;15(4):254. doi: 10.3390/toxins15040254. PMID: 37103986.
* Liew S, Phua C, Khin N, Peh T, Pua V, Lim Z, Loh R. A Review of Botulinum Toxin-A Use in Aesthetic Dermatology. J Clin Aesthet Dermatol. 2023 Aug;16(8):E43-E47. PMID: 37701540.
* Han Y, Hwang S, Park S, Oh K, Kim SW, Song JY, Jeong JY, Jung Y, Kim B, Jung H, Lee J. Adverse effects of botulinum neurotoxin type a in cosmetic practice. J Cosmet Dermatol. 2022 Dec;21(12):6046-6052. doi: 10.1111/jocd.15243. Epub 2022 Sep 27. PMID: 36053919.
* Sathyanarayana S, Chawla A, Singh H, Agrawal A. Immunogenicity of Botulinum Toxin Type A: Clinical Implications and Management. J Clin Aesthet Dermatol. 2020 Jan;13(1):E59-E65. PMID: 32231940.
* Kwon TR, Lee Y, Kim BJ, Kim MN. Prevention and Management of Complications After Aesthetic Botulinum Toxin Injections. J Craniofac Surg. 2020 Jul;31(5):1378-1383. doi: 10.1097/SCS.0000000000006399. PMID: 32443048.
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