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Published on: 3/5/2025

Does Alpha Blockers Work for Benign Prostatic Hyperplasia (BPH) ?

Yes, alpha blockers are an effective treatment for BPH because they help relax the muscles in the prostate and bladder neck, which eases urinary symptoms.

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Explanation

Alpha blockers are a common medicine used to treat benign prostatic hyperplasia (BPH). They work by relaxing the smooth muscles in the prostate and the neck of the bladder. This relaxation helps improve urinary flow and reduces symptoms like difficulty with initiation of urination, a weak stream, and having to go to the bathroom frequently, especially at night. Many studies and clinical guidelines support the use of alpha blockers for BPH, and they are often one of the first treatments a doctor will try to relieve symptoms. They do not shrink the prostate, but by making it easier to urinate, they can greatly improve quality of life. It is important to take alpha blockers as directed and follow up with your doctor to make sure they are working well for you. If you have questions or new symptoms, you should talk to your healthcare provider to decide the best treatment plan for your BPH.

(References)

  • Edwards JL. Diagnosis and management of benign prostatic hyperplasia. _Am Fam Physician_. 2008;77(10):1403-1410.

  • Miernik A, Gratzke C. Current Treatment for Benign Prostatic Hyperplasia. Dtsch Arztebl Int. 2020 Dec 4;117(49):843-854. doi: 10.3238/arztebl.2020.0843. PMID: 33593479; PMCID: PMC8021971.

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