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Published on: 2/24/2026

Short of Breath? Why Your Heart is Struggling: Cardiomyopathy & Medically Approved Next Steps

Shortness of breath during activity or when lying flat can signal cardiomyopathy, a disease that weakens, thickens, or stiffens the heart muscle and can lead to heart failure, fluid buildup, and dangerous arrhythmias.

There are several factors to consider. See below for urgent warning signs, who is at risk, which tests confirm it, and guideline-based treatments and lifestyle steps that can improve outcomes so you can choose the right next steps with your clinician.

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Explanation

Short of Breath? Why Your Heart Is Struggling: Cardiomyopathy & Medically Approved Next Steps

Feeling short of breath can be unsettling—especially if it happens during simple activities like walking across a room or lying flat in bed. While many conditions can cause breathlessness, one serious and often overlooked cause is cardiomyopathy.

Cardiomyopathy is a disease of the heart muscle. When the heart muscle becomes enlarged, thickened, or stiff, it cannot pump blood as effectively as it should. Over time, this can lead to heart failure, irregular heart rhythms, or other complications.

If you're short of breath and wondering whether your heart may be involved, here's what you need to know—based on guidance from leading cardiology organizations and current medical standards.


What Is Cardiomyopathy?

Cardiomyopathy refers to diseases that directly affect the heart muscle. In a healthy heart, the muscle contracts and relaxes efficiently to pump oxygen-rich blood throughout your body. In cardiomyopathy, that function becomes impaired.

There are several main types:

1. Dilated Cardiomyopathy (DCM)

  • The heart chambers enlarge and stretch.
  • The heart becomes weaker and pumps less effectively.
  • This is the most common form.

2. Hypertrophic Cardiomyopathy (HCM)

  • The heart muscle becomes abnormally thick.
  • It can block blood flow or cause electrical problems.
  • Often inherited.

3. Restrictive Cardiomyopathy

  • The heart muscle becomes stiff.
  • The heart cannot fill properly between beats.

4. Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

  • Fatty or fibrous tissue replaces heart muscle.
  • Can cause serious rhythm problems.

Each type of cardiomyopathy affects the heart differently, but all can reduce the heart's ability to supply your body with oxygen-rich blood.


Why Cardiomyopathy Causes Shortness of Breath

Shortness of breath happens when your body isn't getting enough oxygen to meet its needs.

When cardiomyopathy weakens the heart:

  • Blood may back up into the lungs.
  • Fluid can build up.
  • Oxygen delivery decreases.

This leads to symptoms such as:

  • Breathlessness during activity
  • Shortness of breath when lying flat
  • Waking up gasping for air
  • Fatigue
  • Swelling in the legs or abdomen

These are also common signs of heart failure, which often develops as a result of cardiomyopathy.

If you're experiencing any of these warning signs, you can use Ubie's free AI-powered Heart Failure symptom checker to assess your symptoms in just a few minutes and determine whether you should seek medical attention.


Who Is at Risk for Cardiomyopathy?

Cardiomyopathy can affect people of any age. However, certain factors increase your risk:

  • Family history of cardiomyopathy or sudden cardiac death
  • High blood pressure
  • Prior heart attack
  • Coronary artery disease
  • Diabetes
  • Obesity
  • Long-term heavy alcohol use
  • Certain infections
  • Autoimmune conditions
  • Chemotherapy exposure

In some cases, especially hypertrophic cardiomyopathy, genetics play a major role. That's why family screening is often recommended if a close relative has been diagnosed.


Symptoms You Should Not Ignore

Cardiomyopathy can develop slowly. Early on, you may not notice symptoms. But as the condition progresses, signs often appear.

Watch for:

  • Persistent shortness of breath
  • Fatigue that interferes with daily life
  • Swelling in ankles, feet, legs, or abdomen
  • Chest discomfort or pressure
  • Rapid or irregular heartbeat
  • Dizziness or fainting

While these symptoms do not automatically mean you have cardiomyopathy, they do require medical evaluation—especially if they are new, worsening, or severe.

Seek emergency care immediately if you experience:

  • Severe chest pain
  • Sudden collapse
  • Difficulty breathing at rest
  • Fainting during exertion

How Cardiomyopathy Is Diagnosed

Doctors use a combination of tools to diagnose cardiomyopathy.

Common tests include:

  • Echocardiogram (heart ultrasound) – shows heart size, structure, and pumping strength
  • Electrocardiogram (ECG) – detects rhythm abnormalities
  • Cardiac MRI – provides detailed images
  • Blood tests – check for markers of heart strain
  • Genetic testing – in suspected inherited cases
  • Stress testing – evaluates heart function during activity

An echocardiogram is often the most important first test. It can measure ejection fraction, which tells doctors how well your heart pumps blood.


Medically Approved Treatment Options

The good news: Many forms of cardiomyopathy are treatable. While some causes cannot be reversed, modern therapies can significantly improve symptoms and quality of life.

Treatment depends on the type and severity but may include:

Medications

Commonly prescribed drugs include:

  • ACE inhibitors or ARBs – relax blood vessels and reduce strain
  • Beta blockers – slow the heart and improve pumping efficiency
  • Diuretics ("water pills") – reduce fluid buildup
  • Aldosterone antagonists
  • SGLT2 inhibitors (in certain heart failure cases)
  • Blood thinners (if clot risk is present)

These medications are evidence-based and recommended by cardiology guidelines.

Lifestyle Changes

Small changes can make a big difference:

  • Limit sodium (salt) intake
  • Monitor daily weight for fluid changes
  • Stay physically active within doctor-approved limits
  • Avoid heavy alcohol use
  • Stop smoking
  • Maintain a healthy weight

Devices or Procedures

In more advanced cases, doctors may recommend:

  • Implantable cardioverter-defibrillator (ICD)
  • Pacemaker
  • Cardiac resynchronization therapy (CRT)
  • Septal reduction therapy (for certain HCM cases)
  • Heart transplant (rare and reserved for severe cases)

Most patients never need transplant. Early detection and consistent care significantly reduce the risk of severe progression.


Can Cardiomyopathy Be Prevented?

Not all cardiomyopathy can be prevented, especially genetic forms. However, you can reduce your risk by:

  • Controlling blood pressure
  • Managing diabetes
  • Treating coronary artery disease
  • Avoiding excessive alcohol
  • Staying physically active
  • Getting regular check-ups

If cardiomyopathy runs in your family, talk to your doctor about screening—even if you feel well.


When to Speak to a Doctor

If you are experiencing:

  • Ongoing shortness of breath
  • Swelling in your legs
  • Unexplained fatigue
  • Irregular heartbeats
  • Chest discomfort

You should schedule a medical appointment.

If symptoms are sudden or severe, seek emergency care immediately.

Cardiomyopathy can be serious, but early medical care greatly improves outcomes. Modern treatments allow many people to live long, active lives.


A Calm but Clear Takeaway

Shortness of breath should never be ignored—especially if it's new or worsening. While many causes are mild, cardiomyopathy is one condition that deserves careful evaluation.

The key points:

  • Cardiomyopathy affects the heart muscle.
  • It can lead to heart failure if untreated.
  • Symptoms often include breathlessness and fatigue.
  • Early diagnosis improves outcomes.
  • Evidence-based treatments are available and effective.

If you're concerned about your symptoms and want to better understand whether they could be related to Heart Failure, Ubie's free AI-powered symptom checker can help you evaluate your risk and guide your next steps—all before you even pick up the phone to call your doctor.

Most importantly, speak to a doctor about any symptoms that could be serious or life-threatening. Cardiomyopathy is manageable in many cases, especially when caught early. Getting evaluated is not overreacting—it's responsible heart care.

(References)

  • * Heidenreich PA, Bozkurt B, Aguilar D, et al. 2023 ACC/AHA/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. *J Am Coll Cardiol*. 2023;82(15):e17-e243. doi:10.1016/j.jacc.2023.05.018

  • * Elliott P, Anastasakis A, Puerto BT, et al. Cardiomyopathy: classification, diagnosis, and management. *Lancet*. 2021;397(10289):2027-2041. doi:10.1016/S0140-6736(21)00851-0

  • * Russo V, Rago A, Di Natale M, et al. Etiology and prognosis of heart failure in relation to different types of cardiomyopathy. *J Clin Med*. 2021;10(12):2646. doi:10.3390/jcm10122646

  • * Parshall MB, Bittner V. Mechanisms of dyspnea in heart failure. *Heart Fail Rev*. 2019;24(6):877-887. doi:10.1007/s10741-019-09804-0

  • * Maron BJ, Maron MS, Arrighi JA. Cardiomyopathy: a review of current definitions, classification, and approaches to treatment. *World J Cardiol*. 2014;6(11):1108-1120. doi:10.4330/wjc.v6.i11.1108

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