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Published on: 2/24/2026
Shortness of breath during activity or when lying flat can signal cardiomyopathy, a disease that weakens, thickens, or stiffens the heart muscle and can lead to heart failure, fluid buildup, and dangerous arrhythmias.
There are several factors to consider. See below for urgent warning signs, who is at risk, which tests confirm it, and guideline-based treatments and lifestyle steps that can improve outcomes so you can choose the right next steps with your clinician.
Feeling short of breath can be unsettling—especially if it happens during simple activities like walking across a room or lying flat in bed. While many conditions can cause breathlessness, one serious and often overlooked cause is cardiomyopathy.
Cardiomyopathy is a disease of the heart muscle. When the heart muscle becomes enlarged, thickened, or stiff, it cannot pump blood as effectively as it should. Over time, this can lead to heart failure, irregular heart rhythms, or other complications.
If you're short of breath and wondering whether your heart may be involved, here's what you need to know—based on guidance from leading cardiology organizations and current medical standards.
Cardiomyopathy refers to diseases that directly affect the heart muscle. In a healthy heart, the muscle contracts and relaxes efficiently to pump oxygen-rich blood throughout your body. In cardiomyopathy, that function becomes impaired.
There are several main types:
Each type of cardiomyopathy affects the heart differently, but all can reduce the heart's ability to supply your body with oxygen-rich blood.
Shortness of breath happens when your body isn't getting enough oxygen to meet its needs.
When cardiomyopathy weakens the heart:
This leads to symptoms such as:
These are also common signs of heart failure, which often develops as a result of cardiomyopathy.
If you're experiencing any of these warning signs, you can use Ubie's free AI-powered Heart Failure symptom checker to assess your symptoms in just a few minutes and determine whether you should seek medical attention.
Cardiomyopathy can affect people of any age. However, certain factors increase your risk:
In some cases, especially hypertrophic cardiomyopathy, genetics play a major role. That's why family screening is often recommended if a close relative has been diagnosed.
Cardiomyopathy can develop slowly. Early on, you may not notice symptoms. But as the condition progresses, signs often appear.
Watch for:
While these symptoms do not automatically mean you have cardiomyopathy, they do require medical evaluation—especially if they are new, worsening, or severe.
Seek emergency care immediately if you experience:
Doctors use a combination of tools to diagnose cardiomyopathy.
Common tests include:
An echocardiogram is often the most important first test. It can measure ejection fraction, which tells doctors how well your heart pumps blood.
The good news: Many forms of cardiomyopathy are treatable. While some causes cannot be reversed, modern therapies can significantly improve symptoms and quality of life.
Treatment depends on the type and severity but may include:
Commonly prescribed drugs include:
These medications are evidence-based and recommended by cardiology guidelines.
Small changes can make a big difference:
In more advanced cases, doctors may recommend:
Most patients never need transplant. Early detection and consistent care significantly reduce the risk of severe progression.
Not all cardiomyopathy can be prevented, especially genetic forms. However, you can reduce your risk by:
If cardiomyopathy runs in your family, talk to your doctor about screening—even if you feel well.
If you are experiencing:
You should schedule a medical appointment.
If symptoms are sudden or severe, seek emergency care immediately.
Cardiomyopathy can be serious, but early medical care greatly improves outcomes. Modern treatments allow many people to live long, active lives.
Shortness of breath should never be ignored—especially if it's new or worsening. While many causes are mild, cardiomyopathy is one condition that deserves careful evaluation.
The key points:
If you're concerned about your symptoms and want to better understand whether they could be related to Heart Failure, Ubie's free AI-powered symptom checker can help you evaluate your risk and guide your next steps—all before you even pick up the phone to call your doctor.
Most importantly, speak to a doctor about any symptoms that could be serious or life-threatening. Cardiomyopathy is manageable in many cases, especially when caught early. Getting evaluated is not overreacting—it's responsible heart care.
(References)
* Heidenreich PA, Bozkurt B, Aguilar D, et al. 2023 ACC/AHA/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. *J Am Coll Cardiol*. 2023;82(15):e17-e243. doi:10.1016/j.jacc.2023.05.018
* Elliott P, Anastasakis A, Puerto BT, et al. Cardiomyopathy: classification, diagnosis, and management. *Lancet*. 2021;397(10289):2027-2041. doi:10.1016/S0140-6736(21)00851-0
* Russo V, Rago A, Di Natale M, et al. Etiology and prognosis of heart failure in relation to different types of cardiomyopathy. *J Clin Med*. 2021;10(12):2646. doi:10.3390/jcm10122646
* Parshall MB, Bittner V. Mechanisms of dyspnea in heart failure. *Heart Fail Rev*. 2019;24(6):877-887. doi:10.1007/s10741-019-09804-0
* Maron BJ, Maron MS, Arrighi JA. Cardiomyopathy: a review of current definitions, classification, and approaches to treatment. *World J Cardiol*. 2014;6(11):1108-1120. doi:10.4330/wjc.v6.i11.1108
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