Published on: 5/6/2025
Pain at the opening of the urethra can happen for many reasons like infections, injuries, or irritants. This pain might be linked to inflammation, trauma, or conditions that make the urethral tissues sensitive.
There are several things that might cause pain at the urethral opening. One reason is an infection, where germs can get into the urethra and cause swelling and pain. Sometimes people get irritation from chemicals in soaps or lotions, which may hurt the sensitive skin there. Another possibility is an injury from an accident, such as a fall, or even from medical procedures. Inflammation can also happen a clear infection or injury, without leading to pain. Some doctors also talk about a condition called urethral pain syndrome. This condition is when the urethra hurts for a long time even though tests do not show a clear cause. The pain might be worsened by factors like stress or physical pressure from activities. It is important to have a doctor check any ongoing pain to understand the exact cause and find the best way to help you feel better.
(References)
Mehta P, Leslie SW, Reddivari AKR. Dysuria. 2023 Nov 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31751108.
Streltsova O, Kuyarov A, Molvi MSAM, Zubova S, Lazukin V, Tararova E, Kiseleva E. New Approaches in the Study of the Pathogenesis of Urethral Pain Syndrome. Diagnostics (Basel). 2020 Oct 22;10(11):860. doi: 10.3390/diagnostics10110860. PMID: 33105749; PMCID: PMC7690567.
Ivarsson LB, Lindström BE, Olovsson M, Lindström AK. Treatment of Urethral Pain Syndrome (UPS) in Sweden. PLoS One. 2019 Nov 22;14(11):e0225404. doi: 10.1371/journal.pone.0225404. PMID: 31756195; PMCID: PMC6874337.
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